108222

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 2735967..2736606 Replicon chromosome
Accession NZ_CP030926
Organism Peribacillus butanolivorans strain PHB-7a

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag DTO10_RS13170 Protein ID WP_034306610.1
Coordinates 2736256..2736606 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag DTO10_RS13165 Protein ID WP_034306380.1
Coordinates 2735967..2736248 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DTO10_RS13145 2732102..2732692 - 591 WP_098176645.1 rhomboid family intramembrane serine protease -
DTO10_RS13150 2732803..2733159 + 357 WP_116821296.1 holo-ACP synthase -
DTO10_RS13155 2733394..2734398 + 1005 WP_098176644.1 outer membrane lipoprotein carrier protein LolA -
DTO10_RS13160 2734574..2735806 + 1233 WP_180319954.1 alanine racemase -
DTO10_RS13165 2735967..2736248 + 282 WP_034306380.1 antitoxin EndoAI Antitoxin
DTO10_RS13170 2736256..2736606 + 351 WP_034306610.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
DTO10_RS13175 2737097..2737924 + 828 WP_053348281.1 STAS domain-containing protein -
DTO10_RS13180 2737927..2738283 + 357 WP_034306376.1 STAS domain-containing protein -
DTO10_RS13185 2738287..2738688 + 402 WP_053348280.1 anti-sigma regulatory factor -
DTO10_RS13190 2738697..2739707 + 1011 WP_116821298.1 PP2C family protein-serine/threonine phosphatase -
DTO10_RS13195 2739767..2740099 + 333 WP_056526370.1 anti-sigma factor antagonist -
DTO10_RS13200 2740096..2740569 + 474 WP_053348277.1 anti-sigma B factor RsbW -
DTO10_RS13205 2740547..2741332 + 786 WP_056526373.1 RNA polymerase sigma factor SigB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12955.06 Da        Isoelectric Point: 7.2029

>T108222 WP_034306610.1 NZ_CP030926:2736256-2736606 [Peribacillus butanolivorans]
IVVKRGDVYFADLSPVVGSEQGGTRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEPMMQKVNEALQISLGLIEF

Download         Length: 351 bp

>T108222 NZ_CP030926:2736256-2736606 [Peribacillus butanolivorans]
ATTGTTGTTAAGCGTGGTGACGTATACTTCGCAGACCTTTCCCCGGTAGTCGGTTCAGAGCAGGGTGGAACACGTCCGGT
ACTCATTCTACAAAACGATATTGGTAATCGCTTTAGTCCGACTGTGATTGTGGCAGCCATTACAGCTCAAATTCAAAAAG
CGAAATTGCCTACACATGTTGAGATTAATGCGAAAAAGTACGGATTCGAACGAGATTCCGTTATTTTATTAGAACAGATC
CGGACAATTGATAAGCAGCGTTTAACTGATAAAATTACGCATCTTGACGAACCTATGATGCAAAAAGTCAATGAAGCTTT
GCAAATTAGCTTAGGGCTCATTGAGTTTTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10713.13 Da        Isoelectric Point: 5.9054

>AT108222 WP_034306380.1 NZ_CP030926:2735967-2736248 [Peribacillus butanolivorans]
VSESSATREILIRLPQNFLTELDGYASEENVNRSEFIYRATKMYLRERKKKEFRESMKRGYIEMAAINLTIASEAFQAEF
EAGHCVERLVSGG

Download         Length: 282 bp

>AT108222 NZ_CP030926:2735967-2736248 [Peribacillus butanolivorans]
GTGTCTGAATCCAGCGCAACAAGAGAGATATTAATTCGATTACCTCAAAATTTTTTAACTGAGTTAGATGGGTATGCGAG
TGAAGAAAATGTTAATCGCAGTGAATTTATTTATCGTGCCACAAAAATGTATCTTCGCGAACGTAAAAAGAAAGAGTTTC
GTGAATCGATGAAACGCGGTTATATTGAAATGGCGGCCATTAATTTAACGATTGCTTCTGAAGCCTTTCAGGCTGAATTT
GAGGCTGGGCATTGCGTTGAACGATTAGTTAGCGGAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References