Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3255879..3256024 Replicon chromosome
Accession NZ_CP030923
Organism Klebsiella pneumoniae subsp. pneumoniae strain KC-Pl-HB1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3255915..3256017 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3255879..3256024 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DTN91_RS16215 3251009..3253069 + 2061 WP_004899137.1 oligopeptidase B -
DTN91_RS16220 3253073..3253732 - 660 WP_002911407.1 exodeoxyribonuclease X -
DTN91_RS16225 3253811..3254041 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DTN91_RS16230 3254154..3254528 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DTN91_RS16235 3254532..3255401 + 870 WP_004899136.1 copper homeostasis membrane protein CopD -
DTN91_RS16240 3255418..3255756 + 339 WP_002911404.1 YebY family protein -
- 3255879..3256024 - 146 - - Antitoxin
- 3255915..3256017 + 103 - - Toxin
DTN91_RS28100 3256392..3256535 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DTN91_RS16250 3256640..3257608 - 969 WP_004151446.1 VirK/YbjX family protein -
DTN91_RS16255 3257765..3258418 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
DTN91_RS16260 3258415..3258606 - 192 WP_002911395.1 YebW family protein -
DTN91_RS16265 3258704..3258943 - 240 WP_002911393.1 YebV family protein -
DTN91_RS16270 3259059..3260492 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T108209 NZ_CP030923:3255915-3256017 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT108209 NZ_CP030923:c3256024-3255879 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References