Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 844978..846415 Replicon chromosome
Accession NZ_CP030918
Organism Paracoccus suum strain SC2-6

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag DRW48_RS04050 Protein ID WP_114075297.1
Coordinates 844978..845835 (-) Length 286 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag DRW48_RS04055 Protein ID WP_199286152.1
Coordinates 845828..846415 (-) Length 196 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DRW48_RS04020 840328..842031 - 1704 WP_114075293.1 site-specific integrase -
DRW48_RS04025 842196..842402 - 207 WP_114077342.1 helix-turn-helix domain-containing protein -
DRW48_RS04030 842402..842671 - 270 WP_114075294.1 hypothetical protein -
DRW48_RS04035 842800..843012 - 213 WP_114075295.1 hypothetical protein -
DRW48_RS04040 843086..843787 - 702 WP_114075296.1 hypothetical protein -
DRW48_RS04045 843920..844705 - 786 WP_199286151.1 DEAD/DEAH box helicase family protein -
DRW48_RS04050 844978..845835 - 858 WP_114075297.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
DRW48_RS04055 845828..846415 - 588 WP_199286152.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
DRW48_RS04060 846679..846936 - 258 WP_162784669.1 addiction module antitoxin -
DRW48_RS04070 847152..847394 - 243 WP_114077343.1 hypothetical protein -
DRW48_RS04075 847394..847639 - 246 Protein_794 peptidase M15 -
DRW48_RS04080 848366..850480 + 2115 WP_114075301.1 AIPR family protein -
DRW48_RS04085 850612..851052 - 441 WP_114075302.1 restriction endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 839288..860198 20910


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-259)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(11-46)


Sequences

Toxin        


Download         Length: 286 a.a.        Molecular weight: 31228.62 Da        Isoelectric Point: 4.4002

>T108174 WP_114075297.1 NZ_CP030918:c845835-844978 [Paracoccus suum]
MAKQPKDIAASVRQRLLNLARAEGQLFDVVLVAFGLERLVYRLSVSEYRDRFVLKGGMLVTLWTADTGRFTRDIDFLAFG
SDEEAELKTVLSQILAIDGEDGLVYDIESLTAVAIREDQIYGGMRLRTEARLGNTRIPITVDLGFGDALPDPQFEIEYGS
LLDFPAASIRAYSPATVIAEKFQAVVALGLANSRMKDLYDLGTLPKAVNIDMDDLAAAIRGTFARRDTIVPAACPVGLSE
EFSTDPTKTTQWRAYSDGTALEGRPLAEVTAEIWAWLEPACRAAA

Download         Length: 858 bp

>T108174 NZ_CP030918:c845835-844978 [Paracoccus suum]
ATGGCTAAGCAGCCGAAAGATATCGCGGCGTCTGTGCGTCAGCGTCTGCTGAACCTTGCCCGTGCTGAAGGTCAGCTGTT
CGATGTGGTGCTGGTGGCCTTCGGCCTCGAACGACTGGTGTACCGGCTGTCGGTCTCCGAATATCGCGACCGCTTCGTCT
TGAAGGGTGGCATGCTCGTCACCTTGTGGACGGCTGACACCGGCCGCTTTACCCGGGACATCGACTTCTTGGCGTTCGGC
TCGGACGAGGAGGCGGAACTGAAGACTGTCCTCTCCCAGATACTCGCCATAGATGGCGAGGATGGGCTGGTCTATGACAT
TGAAAGCCTGACGGCCGTCGCCATTCGAGAAGACCAGATCTATGGCGGGATGCGGCTCCGGACCGAAGCCCGCTTGGGTA
ACACGCGCATTCCGATCACCGTGGACCTCGGCTTCGGCGACGCCTTGCCCGATCCGCAATTCGAGATCGAGTACGGCTCC
CTGCTCGACTTTCCAGCCGCATCGATCCGCGCCTATTCACCGGCAACGGTCATCGCCGAGAAGTTTCAGGCCGTGGTGGC
GCTGGGCTTGGCGAACAGCCGGATGAAGGATCTCTATGATCTGGGGACGCTGCCGAAGGCCGTCAACATCGACATGGACG
ACCTCGCGGCTGCGATCAGAGGAACCTTCGCTCGACGCGATACGATTGTTCCAGCCGCCTGCCCTGTCGGTCTGTCGGAG
GAGTTCTCGACCGACCCGACAAAGACGACGCAATGGCGGGCTTACTCGGATGGCACGGCTCTCGAGGGACGGCCGCTCGC
GGAGGTCACTGCGGAGATCTGGGCTTGGCTTGAACCGGCATGCAGGGCGGCGGCATGA

Antitoxin


Download         Length: 196 a.a.        Molecular weight: 21328.61 Da        Isoelectric Point: 10.0387

>AT108174 WP_199286152.1 NZ_CP030918:c846415-845828 [Paracoccus suum]
MIDYMEVHAPARSRDLASIGVSGTTIARAVADGVVVRIGRGLYQLPDSEPDLHAGLIEIAKLAPKAVICLTSALSFHQLT
DQLPRRVWIAIGAKDWAPKIEYPRIRIVRFREPYLTNGTEIHRSGDVEVRVYSIAKTIADAFRNPKLVDRSVAIEAMKAA
LSARKATAGQLAAAARENGAWNQMRPYLEALTSNG

Download         Length: 588 bp

>AT108174 NZ_CP030918:c846415-845828 [Paracoccus suum]
ATGATCGACTACATGGAAGTTCATGCGCCAGCCCGTTCAAGGGATCTGGCGTCCATCGGCGTGAGCGGAACCACCATCGC
GAGGGCGGTGGCAGATGGCGTGGTGGTGCGGATCGGGCGGGGACTGTATCAGCTGCCCGACAGCGAGCCCGACCTTCATG
CTGGGCTCATCGAGATCGCCAAACTCGCACCCAAGGCCGTCATCTGCCTGACCTCGGCGCTATCCTTTCATCAGCTGACC
GACCAACTTCCACGCCGGGTGTGGATCGCCATCGGCGCCAAGGACTGGGCACCGAAGATCGAATATCCACGCATCCGCAT
CGTGCGCTTCCGTGAGCCCTACCTGACCAATGGCACCGAGATCCATCGCAGCGGGGACGTGGAGGTCCGAGTCTACTCCA
TAGCCAAGACGATTGCCGACGCATTTCGGAACCCGAAACTTGTAGACCGGTCGGTTGCCATTGAAGCGATGAAGGCCGCG
CTAAGCGCCAGGAAGGCAACGGCAGGCCAGCTTGCTGCAGCCGCTCGCGAGAACGGCGCGTGGAACCAGATGCGCCCCTA
TCTGGAGGCGCTGACATCCAATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References