Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 909641..910224 Replicon chromosome
Accession NZ_CP030871
Organism Acetobacter sp. JWB

Toxin (Protein)


Gene name hicA Uniprot ID F1YT37
Locus tag DS739_RS04380 Protein ID WP_006116155.1
Coordinates 909641..909895 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID F1YT36
Locus tag DS739_RS04385 Protein ID WP_006116153.1
Coordinates 909892..910224 (+) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(23-81)

Antitoxin

Uncharacterised protein family HicB

(56-105)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9479.92 Da        Isoelectric Point: 10.3861

>T108112 WP_006116155.1 NZ_CP030871:909641-909895 [Acetobacter sp. JWB]
MKAKHRRTLELIFKRPVSGNVPWADIEALFVSLGAEVSEREGSRIGVFLFDEVKVFHRPHPKPDTDKGAVASVRKWLEQN
GVTP

Download         Length: 255 bp

>T108112 NZ_CP030871:909641-909895 [Acetobacter sp. JWB]
ATGAAAGCCAAGCACCGCCGCACATTGGAACTGATTTTCAAGCGTCCTGTTTCGGGCAATGTGCCATGGGCAGACATTGA
AGCTTTATTTGTTTCCCTAGGGGCGGAGGTGTCTGAAAGAGAAGGCTCCCGCATAGGGGTGTTCCTGTTTGATGAGGTAA
AGGTGTTTCATAGACCTCACCCCAAACCGGATACAGACAAGGGTGCTGTAGCCTCTGTAAGAAAATGGCTTGAGCAGAAT
GGAGTGACGCCATGA

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 11992.63 Da        Isoelectric Point: 4.6742

>AT108112 WP_006116153.1 NZ_CP030871:909892-910224 [Acetobacter sp. JWB]
MNNVMEIGGHRAVIQFDPEIGMFRGEFLGLNGGADFYADSVAGLQQEGETSLRVFMEMCAEKGIDPVKHYSGRFVVRLPE
DVHARAAEIAAARGISLNRLVQDVLAQVEG

Download         Length: 333 bp

>AT108112 NZ_CP030871:909892-910224 [Acetobacter sp. JWB]
ATGAACAACGTAATGGAAATTGGCGGCCATCGGGCTGTTATTCAGTTTGATCCTGAAATCGGGATGTTCCGGGGTGAGTT
TCTGGGACTGAACGGAGGGGCTGATTTCTACGCAGATAGTGTGGCAGGCCTTCAGCAGGAAGGGGAAACTTCCCTCCGTG
TCTTCATGGAGATGTGTGCTGAGAAAGGCATTGATCCCGTGAAGCATTATTCAGGCCGGTTTGTTGTGAGGCTACCAGAA
GACGTTCATGCACGGGCAGCTGAGATTGCTGCAGCACGCGGGATCAGTCTTAACCGACTGGTGCAGGATGTTTTGGCACA
GGTTGAAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A401X5W6

Antitoxin

Source ID Structure
AlphaFold DB F1YT36

References