Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 673030..673640 Replicon chromosome
Accession NZ_CP030849
Organism Pandoraea sp. XY-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DRB87_RS03065 Protein ID WP_130024822.1
Coordinates 673030..673332 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DRB87_RS03070 Protein ID WP_130024823.1
Coordinates 673329..673640 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DRB87_RS03045 668451..669548 - 1098 WP_130024819.1 branched-chain amino acid aminotransferase -
DRB87_RS03050 669870..670622 - 753 WP_130027687.1 glutathione transferase -
DRB87_RS03055 670768..671817 - 1050 WP_130024820.1 aldo/keto reductase -
DRB87_RS03060 672146..673033 + 888 WP_130024821.1 AraC family transcriptional regulator -
DRB87_RS03065 673030..673332 - 303 WP_130024822.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DRB87_RS03070 673329..673640 - 312 WP_130024823.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DRB87_RS03075 673923..674174 + 252 WP_017232582.1 hypothetical protein -
DRB87_RS03080 674199..675122 - 924 WP_130027688.1 2-hydroxyacid dehydrogenase -
DRB87_RS03085 675399..676742 - 1344 WP_130024824.1 aromatic acid/H+ symport family MFS transporter -
DRB87_RS03090 676952..678169 - 1218 WP_130024825.1 3-hydroxybenzoate 6-monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-50)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11633.36 Da        Isoelectric Point: 11.1832

>T108090 WP_130024822.1 NZ_CP030849:c673332-673030 [Pandoraea sp. XY-2]
VKLEWSQHAIQDRSDIFEYVERFSPNAAIWIDTRIHQQLTTLLRYPAAGRLGRLRGTRELVVTRTPYIAAYRPLPTRVRV
LRILHNAQMWPDTAGTTSPH

Download         Length: 303 bp

>T108090 NZ_CP030849:c673332-673030 [Pandoraea sp. XY-2]
GTGAAATTAGAGTGGTCCCAACACGCGATTCAAGATCGCAGCGATATCTTCGAATACGTCGAGCGATTCAGTCCAAACGC
CGCCATCTGGATAGATACACGCATTCACCAACAACTCACCACGTTGTTGCGGTATCCCGCCGCAGGTCGCCTCGGGCGAT
TGCGCGGCACGCGCGAACTCGTCGTCACGCGCACCCCATACATCGCGGCGTATCGTCCGCTACCCACACGTGTGCGCGTG
CTTCGCATTCTGCATAACGCGCAAATGTGGCCCGACACTGCGGGAACAACGTCGCCACATTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11450.06 Da        Isoelectric Point: 6.4764

>AT108090 WP_130024823.1 NZ_CP030849:c673640-673329 [Pandoraea sp. XY-2]
MATSALVQARIDPELKERATDVLDRMGLTVSDVVRILLTRIANEGALPFGFVADPDAHDAWFKRKVLEALEDTRPAIPDE
DVESHFVARRAAARKRSSPKDKP

Download         Length: 312 bp

>AT108090 NZ_CP030849:c673640-673329 [Pandoraea sp. XY-2]
ATGGCCACTAGCGCACTTGTGCAAGCCCGCATCGATCCCGAACTGAAGGAACGCGCCACCGACGTCCTCGACAGGATGGG
GTTGACCGTCTCCGATGTAGTTCGGATTTTACTCACGCGCATTGCCAACGAAGGTGCGCTACCTTTTGGTTTCGTCGCGG
ATCCTGACGCTCACGATGCATGGTTCAAGCGAAAGGTGCTGGAAGCGCTGGAAGACACACGTCCAGCCATTCCGGATGAA
GACGTCGAATCCCATTTCGTAGCACGCCGTGCCGCCGCACGCAAACGCAGCTCCCCAAAAGATAAGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References