Detailed information of TA system TA108089

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 212999..213634
• Replicon: chromosome
• Accession: NZ_CP030849
• Organism: Pandoraea sp. XY-2

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: DRB87_RS00850
• Protein ID: WP_130024508.1
• Coordinates: 213215..213634 (+)
• Length: 140 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: DRB87_RS00845
• Protein ID: WP_130024507.1
• Coordinates: 212999..213199 (+)
• Length: 67 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DRB87_RS00830	208417..209265	+	849	WP_130024505.1	patatin-like phospholipase family protein	-
DRB87_RS00835	209289..210299	-	1011	WP_130024506.1	D-2-hydroxyacid dehydrogenase family protein	-
DRB87_RS00840	210930..212747	+	1818	WP_130027647.1	phosphoenolpyruvate carboxykinase (GTP)	-
DRB87_RS00845	212999..213199	+	201	WP_130024507.1	DNA-binding protein	Antitoxin
DRB87_RS00850	213215..213634	+	420	WP_130024508.1	type II toxin-antitoxin system VapC family toxin	Toxin
DRB87_RS00855	213709..214341	-	633	WP_130024509.1	response regulator transcription factor	-
DRB87_RS00860	214338..215723	-	1386	WP_130024510.1	cache domain-containing protein	-
DRB87_RS00865	216088..218154	+	2067	WP_130024511.1	carbon starvation protein A	-
DRB87_RS00870	218171..218368	+	198	WP_130024512.1	YbdD/YjiX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-128)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 140 a.a.
• Molecular weight: 16058.52 Da
• Isoelectric Point: 9.6515

>T108089 WP_130024508.1 NZ_CP030849:213215-213634 [Pandoraea sp. XY-2]
MYLLDTNVISECRKCGGGDEGVQRFIRRTDRDQSPRFLSVITLGELQRGVKVLRHRNDARQAVLIETWLEKLKRDYAREI
LPVDQTICNVWARLRVPHSEHPIDKLIAATALVHRLVVVTRNVKDFSNTGVEVYNPFVH

Nucleotide

• Length: 420 bp

>T108089 NZ_CP030849:213215-213634 [Pandoraea sp. XY-2]
ATGTATTTACTCGATACGAACGTTATTAGCGAGTGTCGGAAATGTGGGGGCGGTGACGAAGGGGTCCAGCGCTTTATCCG
TCGGACCGATCGTGATCAATCACCGCGCTTTCTTTCGGTCATCACACTGGGGGAACTACAGCGTGGTGTGAAAGTCCTTC
GGCACCGGAATGATGCGCGACAGGCGGTGTTGATCGAGACATGGCTCGAGAAGCTGAAACGCGATTACGCGCGCGAGATT
TTGCCGGTGGACCAGACGATCTGTAACGTTTGGGCACGTCTGCGCGTGCCCCATTCCGAGCACCCCATCGACAAGTTGAT
CGCCGCCACTGCGCTGGTGCATCGGCTTGTCGTGGTCACGCGCAACGTGAAGGATTTTTCCAATACCGGCGTGGAGGTAT
ACAACCCATTTGTGCACTGA

Antitoxin

Protein

• Length: 67 a.a.
• Molecular weight: 7378.54 Da
• Isoelectric Point: 4.3021

>AT108089 WP_130024507.1 NZ_CP030849:212999-213199 [Pandoraea sp. XY-2]
MMLIEGIDEPLMRSIRSRAAMYGRTPEEEVLTILDNVARVPGFRSLGEALLAMPNVGLDSDFERIN

Nucleotide

• Length: 201 bp

>AT108089 NZ_CP030849:212999-213199 [Pandoraea sp. XY-2]
ATGATGTTGATCGAAGGTATTGACGAACCGCTCATGCGATCGATACGGTCGCGTGCGGCCATGTACGGGAGAACCCCGGA
GGAAGAAGTGCTGACGATTCTGGATAACGTGGCGCGGGTTCCCGGGTTTCGCTCGCTGGGGGAAGCACTGTTGGCCATGC
CGAATGTTGGACTGGACAGCGATTTTGAACGTATCAATTAA