108087

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 5379392..5380077 Replicon chromosome
Accession NZ_CP030840
Organism Acidisarcina polymorpha strain SBC82

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ACPOL_RS22850 Protein ID WP_114209102.1
Coordinates 5379634..5380077 (+) Length 148 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ACPOL_RS22845 Protein ID WP_114209101.1
Coordinates 5379392..5379637 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACPOL_RS22825 5374547..5375848 + 1302 WP_114209097.1 DNA polymerase -
ACPOL_RS22830 5376007..5376945 + 939 WP_114209098.1 N-acetylmuramic acid 6-phosphate etherase -
ACPOL_RS22835 5377050..5377799 + 750 WP_161557522.1 isoprenylcysteine carboxylmethyltransferase family protein -
ACPOL_RS22840 5377835..5379232 - 1398 WP_114209100.1 replicative DNA helicase -
ACPOL_RS22845 5379392..5379637 + 246 WP_114209101.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ACPOL_RS22850 5379634..5380077 + 444 WP_114209102.1 type II toxin-antitoxin system VapC family toxin Toxin
ACPOL_RS22855 5380214..5380840 + 627 WP_161557523.1 nuclear transport factor 2 family protein -
ACPOL_RS22860 5380854..5382833 - 1980 WP_114209104.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG -
ACPOL_RS22865 5382903..5383664 - 762 WP_161557524.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-66)


Sequences

Toxin        


Download         Length: 148 a.a.        Molecular weight: 16249.50 Da        Isoelectric Point: 8.5229

>T108087 WP_114209102.1 NZ_CP030840:5379634-5380077 [Acidisarcina polymorpha]
MSGRRLQYLLDTNVLSETRKKQADAQVIRFLSSADPSTLYISVLTLGELRKGVALKQHSDPDAAKQIGHWVDGLEYSFAD
RILGIDAATARLWGELSAQRPRPVIDTLLAATALSHELTFVTRNMSDVSDIQMQRLDPWKSNAAGAK

Download         Length: 444 bp

>T108087 NZ_CP030840:5379634-5380077 [Acidisarcina polymorpha]
TTGAGTGGGCGGCGACTTCAATACCTGCTCGACACGAATGTCCTATCGGAGACGCGCAAGAAACAGGCCGACGCTCAAGT
TATTAGGTTCCTGAGTTCGGCTGACCCGTCGACGCTCTATATAAGCGTTTTGACGCTGGGGGAGTTGAGGAAGGGAGTGG
CGCTCAAGCAACACTCCGATCCGGACGCTGCGAAGCAGATCGGCCACTGGGTGGATGGACTGGAATACAGCTTCGCGGAC
CGCATCCTGGGCATCGACGCCGCGACGGCGCGGCTGTGGGGGGAGTTGTCGGCGCAGCGTCCCAGGCCGGTGATCGACAC
GCTATTGGCGGCAACCGCGTTGTCGCATGAGTTGACCTTCGTGACTCGCAACATGAGCGATGTGTCGGACATTCAGATGC
AGCGACTTGATCCCTGGAAAAGTAACGCGGCCGGTGCAAAATAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9149.43 Da        Isoelectric Point: 5.1358

>AT108087 WP_114209101.1 NZ_CP030840:5379392-5379637 [Acidisarcina polymorpha]
MASWQMQEAKTRLSEVIEEASKKGPQIITRHGAERAVILSMADYRALTAHKPDLRDYLLGGPKLDDFEIERDLDPGREIG
L

Download         Length: 246 bp

>AT108087 NZ_CP030840:5379392-5379637 [Acidisarcina polymorpha]
ATGGCCAGTTGGCAGATGCAAGAAGCGAAGACCCGGCTGAGTGAAGTGATTGAGGAAGCTTCAAAGAAGGGGCCGCAGAT
CATTACCAGGCACGGGGCGGAACGAGCGGTGATTCTCTCCATGGCGGACTATCGCGCGCTCACCGCCCACAAACCCGACT
TAAGAGATTATCTGCTGGGAGGGCCGAAGCTGGATGACTTCGAGATCGAACGTGACCTTGATCCGGGCAGAGAGATTGGC
CTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References