Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4862966..4863237 Replicon chromosome
Accession NZ_CP030768
Organism Escherichia coli strain 2017C-4173W12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4863004..4863107 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4862966..4863237 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSB71_RS25450 4860123..4861562 + 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DSB71_RS25455 4861680..4861916 + 237 WP_001295499.1 DUF1480 family protein -
DSB71_RS25460 4862021..4862212 + 192 WP_001296140.1 YebW family protein -
DSB71_RS25465 4862213..4862869 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 4862966..4863237 + 272 - - Antitoxin
- 4863004..4863107 - 104 - - Toxin
DSB71_RS25470 4863265..4863606 - 342 WP_000976481.1 YebY family protein -
DSB71_RS25475 4863619..4864491 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
DSB71_RS25480 4864495..4864869 - 375 WP_000204705.1 CopC domain-containing protein YobA -
DSB71_RS25485 4865008..4865238 + 231 WP_000916763.1 DNA polymerase III subunit theta -
DSB71_RS25490 4865340..4865996 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
DSB71_RS25495 4866020..4866682 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4846415..4887024 40609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T107918 NZ_CP030768:c4863107-4863004 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT107918 NZ_CP030768:4862966-4863237 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References