Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1985101..1985372 Replicon chromosome
Accession NZ_CP030767
Organism Escherichia coli strain 2017C-4109

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1985139..1985242 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1985101..1985372 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSB73_RS11130 1982258..1983697 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DSB73_RS11135 1983815..1984051 + 237 WP_001295499.1 DUF1480 family protein -
DSB73_RS11140 1984156..1984347 + 192 WP_001296140.1 YebW family protein -
DSB73_RS11145 1984348..1985004 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 1985101..1985372 + 272 - - Antitoxin
- 1985139..1985242 - 104 - - Toxin
DSB73_RS11150 1985400..1985741 - 342 WP_000976483.1 YebY family protein -
DSB73_RS11155 1985754..1986626 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
DSB73_RS11160 1986630..1987004 - 375 WP_000168751.1 CopC domain-containing protein YobA -
DSB73_RS11165 1987143..1987373 + 231 WP_000916763.1 DNA polymerase III subunit theta -
DSB73_RS11170 1987475..1988131 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
DSB73_RS11175 1988155..1988817 + 663 WP_000944244.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T107865 NZ_CP030767:c1985242-1985139 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT107865 NZ_CP030767:1985101-1985372 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References