Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 7451..7983 Replicon plasmid unnamed3
Accession NZ_CP030763
Organism Rhizobium leguminosarum strain ATCC 14479

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag DLJ82_RS32405 Protein ID WP_112907866.1
Coordinates 7690..7983 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag DLJ82_RS32400 Protein ID WP_112907865.1
Coordinates 7451..7693 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLJ82_RS32370 2894..3544 - 651 WP_112907859.1 Rieske 2Fe-2S domain-containing protein -
DLJ82_RS32375 3700..3966 - 267 WP_112907860.1 acylphosphatase -
DLJ82_RS32380 4306..4536 + 231 WP_112907861.1 hypothetical protein -
DLJ82_RS32385 4566..5459 - 894 WP_112907862.1 LysR family transcriptional regulator -
DLJ82_RS32390 5575..6207 + 633 WP_112907863.1 DsbA family protein -
DLJ82_RS32395 6283..7185 + 903 WP_162710382.1 MBL fold metallo-hydrolase -
DLJ82_RS32400 7451..7693 + 243 WP_112907865.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
DLJ82_RS32405 7690..7983 + 294 WP_112907866.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DLJ82_RS32410 8371..9768 - 1398 WP_112907867.1 dihydrolipoyl dehydrogenase -
DLJ82_RS32415 9774..11021 - 1248 WP_112907868.1 2-oxo acid dehydrogenase subunit E2 -
DLJ82_RS32420 11025..12038 - 1014 WP_112907869.1 alpha-ketoacid dehydrogenase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - gmd 1..771583 771583


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11243.78 Da        Isoelectric Point: 4.9230

>T107851 WP_112907866.1 NZ_CP030763:7690-7983 [Rhizobium leguminosarum]
MSFKLSAEAEEDIIAIAEQGVRMFGAGQAKRYHDELFALFDLIAVNPRIARERDEIDPPVRIHPFKAHLIVYRIEDDETI
FVIRIRHAHEDWASDSI

Download         Length: 294 bp

>T107851 NZ_CP030763:7690-7983 [Rhizobium leguminosarum]
ATGAGTTTTAAGCTTTCTGCCGAAGCGGAAGAGGACATTATTGCGATCGCCGAGCAAGGTGTCCGTATGTTCGGGGCAGG
CCAGGCAAAGCGATACCACGATGAACTTTTCGCATTATTTGATCTGATAGCTGTCAATCCACGCATCGCGCGCGAACGGG
ATGAGATTGATCCGCCCGTTAGAATTCATCCCTTCAAAGCGCATCTAATCGTTTATCGGATCGAAGATGATGAGACAATT
TTTGTAATACGAATTCGCCACGCGCATGAAGATTGGGCAAGTGATTCAATTTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8811.92 Da        Isoelectric Point: 9.7765

>AT107851 WP_112907865.1 NZ_CP030763:7451-7693 [Rhizobium leguminosarum]
MATMNVSLPGPMKDWVEAQARTGRYSNASDYVRDLIRRDQTRNDKIAAMQSFVEAGLQGGVGTRSKDELFAEAMARASKS

Download         Length: 243 bp

>AT107851 NZ_CP030763:7451-7693 [Rhizobium leguminosarum]
ATGGCCACGATGAACGTATCTCTTCCAGGCCCGATGAAGGATTGGGTGGAGGCCCAGGCCAGGACCGGGCGATATTCTAA
TGCTAGCGACTACGTGCGCGACCTGATCCGACGCGACCAGACGCGAAACGACAAGATCGCCGCCATGCAAAGCTTCGTCG
AGGCCGGGCTCCAAGGTGGTGTCGGCACCCGATCAAAGGATGAACTCTTTGCTGAGGCGATGGCTCGTGCCAGCAAGTCA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References