Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 115119..115762 Replicon plasmid unnamed2
Accession NZ_CP030762
Organism Rhizobium leguminosarum strain ATCC 14479

Toxin (Protein)


Gene name vapC Uniprot ID A0A2Z4YRA4
Locus tag DLJ82_RS30790 Protein ID WP_063473325.1
Coordinates 115376..115762 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID Q1WLI3
Locus tag DLJ82_RS30785 Protein ID WP_012881219.1
Coordinates 115119..115376 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLJ82_RS30765 110315..110986 - 672 WP_063473328.1 HAD family hydrolase -
DLJ82_RS30770 111122..112408 - 1287 WP_063473327.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
DLJ82_RS30775 112851..114125 + 1275 WP_063473326.1 ROK family protein -
DLJ82_RS30780 114311..114999 + 689 Protein_113 IS6 family transposase -
DLJ82_RS30785 115119..115376 + 258 WP_012881219.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
DLJ82_RS30790 115376..115762 + 387 WP_063473325.1 type II toxin-antitoxin system VapC family toxin Toxin
DLJ82_RS30800 116199..116907 + 709 Protein_116 IS6 family transposase -
DLJ82_RS30820 117734..118000 + 267 WP_027690734.1 hypothetical protein -
DLJ82_RS30825 118088..119578 + 1491 WP_063473767.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..415988 415988


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(2-84)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14064.31 Da        Isoelectric Point: 4.5849

>T107850 WP_063473325.1 NZ_CP030762:115376-115762 [Rhizobium leguminosarum]
MVMDTSAIVAILRNEPEAAKLERSLVANPVRLVPATCVLEARMVLVSRRGEHALAEIDLWLSKIEADIISVDSDLVDLAT
QAWLIYGKGRHPAALNFADCFSYALAKRADEPLLFIGKDFLQTDIEAA

Download         Length: 387 bp

>T107850 NZ_CP030762:115376-115762 [Rhizobium leguminosarum]
ATGGTGATGGATACCTCCGCCATCGTGGCGATTCTGCGTAACGAGCCGGAAGCGGCCAAGCTCGAAAGGTCGCTCGTCGC
CAACCCAGTTCGGCTTGTCCCTGCGACGTGTGTGCTCGAGGCGCGCATGGTGCTGGTCAGCCGGCGCGGAGAACACGCAC
TGGCCGAAATCGATCTTTGGCTTAGCAAAATCGAGGCTGACATCATCTCTGTCGATTCTGATCTGGTCGATTTGGCGACG
CAGGCCTGGCTGATCTACGGCAAGGGCCGCCATCCGGCGGCTTTGAATTTTGCCGACTGCTTTTCCTACGCTTTGGCAAA
GCGTGCGGACGAACCGCTTCTCTTCATCGGCAAGGACTTTTTGCAAACCGATATCGAGGCGGCGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9474.69 Da        Isoelectric Point: 6.8806

>AT107850 WP_012881219.1 NZ_CP030762:115119-115376 [Rhizobium leguminosarum]
VSLNIKNPATVALADELARRQGISKTAAIHQALSERLHRMGHGEVSQDRLLGELRAIRQRIARLPELDSRSDEEIIGYDE
HGIPN

Download         Length: 258 bp

>AT107850 NZ_CP030762:115119-115376 [Rhizobium leguminosarum]
GTGTCGCTGAACATCAAAAATCCAGCCACTGTAGCGCTCGCTGACGAACTGGCGCGCCGCCAAGGAATCAGCAAGACGGC
AGCCATCCATCAGGCCCTAAGCGAACGTCTCCACCGTATGGGTCACGGGGAGGTCTCCCAGGATCGTCTGCTCGGCGAAT
TACGCGCTATCCGGCAAAGGATAGCACGTCTTCCGGAATTGGACAGTCGCAGTGACGAGGAGATCATCGGATATGACGAG
CATGGAATTCCGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2Z4YRA4

Antitoxin

Source ID Structure
AlphaFold DB A0A2Z4YSJ3

References