Detailed information of TA system TA107840

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 403145..403769
• Replicon: chromosome
• Accession: NZ_CP030754
• Organism: Acinetobacter schindleri strain H3

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A1J4NJK9
• Locus tag: DPR03_RS02015
• Protein ID: WP_071319858.1
• Coordinates: 403383..403769 (+)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: DPR03_RS02010
• Protein ID: WP_171056625.1
• Coordinates: 403145..403390 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DPR03_RS01990	398604..399611	+	1008	WP_004809777.1	DNA-directed RNA polymerase subunit alpha	-
DPR03_RS01995	399630..399995	+	366	WP_004786886.1	50S ribosomal protein L17	-
DPR03_RS02000	400215..401720	+	1506	WP_071319856.1	NAD(P)/FAD-dependent oxidoreductase	-
DPR03_RS02005	401784..402956	-	1173	WP_071319857.1	acyl-CoA dehydrogenase family protein	-
DPR03_RS02010	403145..403390	+	246	WP_171056625.1	succinate dehydrogenase assembly factor 2	Antitoxin
DPR03_RS02015	403383..403769	+	387	WP_071319858.1	hypothetical protein	Toxin
DPR03_RS02020	404305..405345	+	1041	WP_034592054.1	hypothetical protein	-
DPR03_RS02025	405411..405983	+	573	WP_048881851.1	rhombosortase	-
DPR03_RS02030	406160..408355	+	2196	WP_071319859.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (7-126)

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15509.54 Da
• Isoelectric Point: 9.6431

>T107840 WP_071319858.1 NZ_CP030754:403383-403769 [Acinetobacter schindleri]
MDSRCYQLKRSLLALAFQFFIFIVLMFVMYQLLPLWLWGICLVAGLIIYHLFYRKRPQIAQFEYLDGREWTITHHDQRIQ
RAQISHVIDHQAYLVVYFQHAKIPPLLIWCDQLPTQQWKSLKVLTKMI

Nucleotide

• Length: 387 bp

>T107840 NZ_CP030754:403383-403769 [Acinetobacter schindleri]
ATGGATAGTCGTTGTTATCAGCTGAAACGCAGCCTGCTTGCACTTGCGTTTCAGTTTTTCATTTTTATTGTGTTGATGTT
TGTGATGTACCAGTTATTGCCCTTATGGCTATGGGGAATCTGTCTGGTTGCAGGACTGATCATCTATCATCTGTTTTATC
GCAAGCGTCCGCAGATCGCCCAGTTTGAATATCTGGATGGTCGGGAATGGACCATTACCCATCATGATCAGCGCATACAG
CGTGCCCAGATCAGTCATGTGATTGATCACCAAGCTTATCTGGTGGTGTATTTTCAGCATGCCAAAATACCGCCATTGCT
GATCTGGTGTGACCAGTTACCAACACAACAATGGAAGTCATTGAAAGTCCTTACGAAAATGATCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9778.20 Da
• Isoelectric Point: 4.7118

>AT107840 WP_171056625.1 NZ_CP030754:403145-403390 [Acinetobacter schindleri]
ISLEERKVIYRARRGLKELDVYFDPYVKNCYLTADPFEKEMFAELVAQEDPDLLDWFMEVSEPPRPELREFINKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT107840 NZ_CP030754:403145-403390 [Acinetobacter schindleri]
ATCAGCCTGGAAGAGCGTAAAGTGATTTACCGCGCACGTCGTGGTCTTAAAGAGTTGGATGTGTATTTTGATCCCTATGT
CAAAAACTGCTATTTGACAGCAGACCCATTTGAAAAAGAAATGTTTGCTGAACTCGTAGCGCAAGAAGACCCGGACCTGC
TGGACTGGTTTATGGAAGTATCCGAACCGCCACGTCCTGAATTACGTGAGTTTATTAACAAGCTTAAACACTACGTTCAT
GGATAG

Structures

Toxin

• AlphaFold DB: A0A1J4NJK9