Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 975982..977501 Replicon chromosome
Accession NZ_CP030352
Organism Novosphingobium sp. P6W

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag TQ38_RS04790 Protein ID WP_043979946.1
Coordinates 976587..977501 (+) Length 305 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag TQ38_RS04785 Protein ID WP_082057957.1
Coordinates 975982..976590 (+) Length 203 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TQ38_RS04755 971033..971839 - 807 WP_162792209.1 abortive infection family protein -
TQ38_RS04760 972270..972827 + 558 WP_052506001.1 hypothetical protein -
TQ38_RS04765 973045..973950 + 906 WP_043979939.1 site-specific integrase -
TQ38_RS04770 973955..975148 + 1194 WP_043979941.1 IS91 family transposase -
TQ38_RS30530 975641..975715 - 75 WP_205316099.1 hypothetical protein -
TQ38_RS04785 975982..976590 + 609 WP_082057957.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
TQ38_RS04790 976587..977501 + 915 WP_043979946.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
TQ38_RS04795 978433..978654 + 222 WP_043979948.1 AlpA family phage regulatory protein -
TQ38_RS04800 978942..979550 + 609 WP_043979950.1 hypothetical protein -
TQ38_RS04805 979543..980595 + 1053 WP_043979953.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
TQ38_RS04810 981104..982276 + 1173 WP_043979955.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 871715..980921 109206


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-52)


Sequences

Toxin        


Download         Length: 305 a.a.        Molecular weight: 33518.59 Da        Isoelectric Point: 5.0798

>T107824 WP_043979946.1 NZ_CP030352:976587-977501 [Novosphingobium sp. P6W]
MSRPPKNMAISVRDRLTGRARERRENAQLLMTRYVIERLLFRLSLSPHRERFVLKGAMLFSLWAEAPYRATGDLDLLGIG
ENAPEQLEAVFQEILGVAVDDDGIVFRPETLRAAAARAEDEYAGVRIDFVAELAGARLPMHVDIGYGDAITPAAIEIEYP
SLLGQPTAYLRAYPPETVVAEKFQAMVALGMLNTRLKDFYDIWAIAGSFAFDGAVLSRAIQATFDRRQTPLPVETPPALK
PAFADEKQGQWTAFLRRTEIALAPEPFAAIQGQIASLVMPPVLALGQGTALASDWPIGGPWKDR

Download         Length: 915 bp

>T107824 NZ_CP030352:976587-977501 [Novosphingobium sp. P6W]
ATGAGCCGACCGCCGAAGAACATGGCGATCTCGGTGCGCGACCGGCTGACGGGGCGCGCCCGCGAGCGCCGGGAAAACGC
ACAGCTGCTTATGACCCGCTACGTCATCGAACGCCTCCTGTTCCGCTTGAGCCTGTCGCCCCATCGCGAGCGGTTCGTGC
TAAAGGGCGCGATGCTGTTCAGCCTGTGGGCAGAAGCCCCCTATCGCGCCACCGGCGACCTCGATCTGCTCGGCATCGGC
GAGAACGCGCCCGAGCAGCTCGAGGCGGTGTTTCAGGAAATTCTTGGCGTCGCAGTCGATGACGACGGTATCGTGTTCCG
GCCCGAAACCCTGCGCGCGGCCGCAGCCCGTGCCGAGGATGAATATGCCGGCGTCCGTATCGACTTCGTTGCCGAACTCG
CGGGCGCGCGCCTGCCGATGCATGTCGATATCGGCTATGGTGACGCGATCACGCCGGCCGCGATCGAGATCGAGTATCCG
TCGCTGCTAGGCCAACCCACCGCGTATCTTCGGGCTTATCCGCCTGAAACGGTCGTGGCTGAGAAATTCCAGGCAATGGT
CGCACTCGGCATGCTGAACACGCGCCTGAAGGATTTCTACGACATCTGGGCGATCGCGGGATCGTTTGCGTTCGATGGCG
CTGTGTTGTCGCGCGCCATCCAGGCGACCTTCGATCGCCGCCAAACCCCGTTGCCCGTCGAGACGCCCCCCGCGCTCAAG
CCCGCCTTCGCCGACGAAAAGCAGGGCCAATGGACAGCGTTTCTGCGGCGGACCGAAATCGCGTTGGCGCCCGAACCGTT
CGCGGCAATCCAGGGGCAAATCGCGTCGCTCGTGATGCCGCCGGTGCTGGCGCTCGGCCAAGGCACCGCCTTGGCCAGCG
ACTGGCCCATTGGCGGTCCCTGGAAGGACAGGTAA

Antitoxin


Download         Length: 203 a.a.        Molecular weight: 22327.89 Da        Isoelectric Point: 9.8125

>AT107824 WP_082057957.1 NZ_CP030352:975982-976590 [Novosphingobium sp. P6W]
MKLTTHRERALEVVRHCGIARGRDFDAAGVTRATLQRLRNEGVLQQVGRGLYKLADADVDSATSLAEAVRIQPRGVICLL
SALQFHELTTQTPHAVWMMLGQKEWAPVNPSVALKIVRASGEALTAGVETHVIDGVPVPITVPAKTVADCFKHRNKIGID
VAVEALRDFMKSRPRPDLNAIYRYAQLDRVQSVIRPYLEAMT

Download         Length: 609 bp

>AT107824 NZ_CP030352:975982-976590 [Novosphingobium sp. P6W]
ATGAAACTGACGACTCATCGAGAGCGGGCCCTAGAGGTCGTCCGGCACTGCGGCATCGCGCGGGGGCGTGATTTCGACGC
GGCCGGCGTCACGCGGGCGACCCTGCAAAGGCTGCGTAACGAAGGCGTCCTCCAGCAGGTCGGCCGCGGCCTCTACAAGC
TGGCCGATGCTGATGTCGACAGCGCGACGAGCCTGGCTGAGGCCGTGCGTATCCAGCCGCGCGGCGTCATCTGCCTGCTC
TCGGCACTGCAATTTCACGAGCTGACCACGCAGACCCCCCACGCGGTGTGGATGATGCTCGGCCAAAAAGAGTGGGCACC
GGTCAATCCGTCGGTGGCGCTGAAGATCGTTCGCGCGAGCGGCGAAGCTCTGACAGCGGGCGTGGAGACACATGTCATCG
ACGGCGTTCCCGTGCCCATCACCGTACCGGCCAAAACCGTCGCCGACTGCTTCAAGCACCGCAACAAGATCGGTATCGAC
GTCGCGGTCGAGGCGCTGCGTGATTTCATGAAGTCTCGACCCCGGCCGGACCTCAATGCGATCTACCGTTATGCCCAGCT
CGATCGGGTCCAATCGGTGATCCGGCCCTATCTCGAAGCCATGACATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References