Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1990533..1990804 Replicon chromosome
Accession NZ_CP030331
Organism Escherichia coli strain AR_452

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1990663..1990766 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1990533..1990804 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC39_RS11105 1987088..1987750 - 663 WP_000944256.1 exodeoxyribonuclease X -
CSC39_RS11110 1987774..1988430 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CSC39_RS11115 1988532..1988762 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CSC39_RS11120 1988901..1989275 + 375 WP_000204699.1 CopC domain-containing protein YobA -
CSC39_RS11125 1989279..1990151 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
CSC39_RS11130 1990164..1990505 + 342 WP_000976472.1 YebY family protein -
- 1990533..1990804 - 272 - - Antitoxin
- 1990663..1990766 + 104 - - Toxin
CSC39_RS11135 1990901..1991557 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
CSC39_RS11140 1991558..1991749 - 192 WP_001296140.1 YebW family protein -
CSC39_RS11145 1991854..1992090 - 237 WP_001295499.1 DUF1480 family protein -
CSC39_RS11150 1992208..1993647 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T107726 NZ_CP030331:1990663-1990766 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT107726 NZ_CP030331:c1990804-1990533 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References