Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1952760..1952905 Replicon chromosome
Accession NZ_CP030315
Organism Klebsiella pneumoniae strain 11305

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1952796..1952898 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1952760..1952905 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DRB03_RS09510 1947890..1949950 + 2061 WP_004151449.1 oligopeptidase B -
DRB03_RS09515 1949954..1950613 - 660 WP_002911407.1 exodeoxyribonuclease X -
DRB03_RS09520 1950692..1950922 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DRB03_RS09525 1951035..1951409 + 375 WP_039819395.1 CopC domain-containing protein YobA -
DRB03_RS09530 1951413..1952282 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
DRB03_RS09535 1952299..1952637 + 339 WP_002911404.1 YebY family protein -
- 1952760..1952905 - 146 - - Antitoxin
- 1952796..1952898 + 103 - - Toxin
DRB03_RS09540 1953274..1953417 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
DRB03_RS09545 1953522..1954490 - 969 WP_014907334.1 VirK/YbjX family protein -
DRB03_RS09550 1954647..1955300 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
DRB03_RS09555 1955297..1955488 - 192 WP_002911395.1 YebW family protein -
DRB03_RS09560 1955586..1955825 - 240 WP_002911393.1 YebV family protein -
DRB03_RS09565 1955941..1957374 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T107636 NZ_CP030315:1952796-1952898 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT107636 NZ_CP030315:c1952905-1952760 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References