Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1882605..1882750 Replicon chromosome
Accession NZ_CP030313
Organism Klebsiella pneumoniae strain 11311

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1882641..1882743 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1882605..1882750 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DRA79_RS09050 (DRA79_09320) 1877735..1879795 + 2061 WP_004151449.1 oligopeptidase B -
DRA79_RS09055 (DRA79_09325) 1879799..1880458 - 660 WP_002911407.1 exodeoxyribonuclease X -
DRA79_RS09060 (DRA79_09330) 1880537..1880767 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DRA79_RS09065 (DRA79_09335) 1880880..1881254 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DRA79_RS09070 (DRA79_09340) 1881258..1882127 + 870 WP_048331959.1 copper homeostasis membrane protein CopD -
DRA79_RS09075 (DRA79_09345) 1882144..1882482 + 339 WP_016529031.1 YebY family protein -
- 1882605..1882750 - 146 - - Antitoxin
- 1882641..1882743 + 103 - - Toxin
DRA79_RS09080 1883119..1883262 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DRA79_RS09085 (DRA79_09355) 1883367..1884335 - 969 WP_074185275.1 VirK/YbjX family protein -
DRA79_RS09090 (DRA79_09360) 1884492..1885145 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
DRA79_RS09095 (DRA79_09365) 1885142..1885333 - 192 WP_002911395.1 YebW family protein -
DRA79_RS09100 (DRA79_09370) 1885431..1885670 - 240 WP_002911393.1 YebV family protein -
DRA79_RS09105 (DRA79_09375) 1885786..1887219 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T107614 NZ_CP030313:1882641-1882743 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT107614 NZ_CP030313:c1882750-1882605 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References