Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1888203..1888348 Replicon chromosome
Accession NZ_CP030302
Organism Klebsiella pneumoniae strain 205880

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1888239..1888341 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1888203..1888348 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DRB04_RS09080 (DRB04_09325) 1883333..1885393 + 2061 WP_004151449.1 oligopeptidase B -
DRB04_RS09085 (DRB04_09330) 1885397..1886056 - 660 WP_004145547.1 exodeoxyribonuclease X -
DRB04_RS09090 (DRB04_09335) 1886135..1886365 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DRB04_RS09095 (DRB04_09340) 1886478..1886852 + 375 WP_016529032.1 CopC domain-containing protein YobA -
DRB04_RS09100 (DRB04_09345) 1886856..1887725 + 870 WP_065888599.1 copper homeostasis membrane protein CopD -
DRB04_RS09105 (DRB04_09350) 1887742..1888080 + 339 WP_065888598.1 YebY family protein -
- 1888203..1888348 - 146 - - Antitoxin
- 1888239..1888341 + 103 - - Toxin
DRB04_RS09110 1888716..1888859 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DRB04_RS09115 (DRB04_09360) 1888964..1889932 - 969 WP_004151446.1 VirK/YbjX family protein -
DRB04_RS09120 (DRB04_09365) 1890089..1890742 + 654 WP_014343242.1 protein-serine/threonine phosphatase -
DRB04_RS09125 (DRB04_09370) 1890739..1890930 - 192 WP_002911395.1 YebW family protein -
DRB04_RS09130 (DRB04_09375) 1891028..1891267 - 240 WP_002911393.1 YebV family protein -
DRB04_RS09135 (DRB04_09380) 1891383..1892816 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T107565 NZ_CP030302:1888239-1888341 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT107565 NZ_CP030302:c1888348-1888203 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References