Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1997688..1997833 Replicon chromosome
Accession NZ_CP030296
Organism Klebsiella pneumoniae strain 309074

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1997724..1997826 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1997688..1997833 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQG43_RS09705 1992818..1994878 + 2061 WP_004151449.1 oligopeptidase B -
DQG43_RS09710 1994882..1995541 - 660 WP_021440386.1 exodeoxyribonuclease X -
DQG43_RS09715 1995620..1995850 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DQG43_RS09720 1995963..1996337 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DQG43_RS09725 1996341..1997210 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
DQG43_RS09730 1997227..1997565 + 339 WP_002911404.1 YebY family protein -
- 1997688..1997833 - 146 - - Antitoxin
- 1997724..1997826 + 103 - - Toxin
DQG43_RS09735 1998202..1998345 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DQG43_RS09740 1998450..1999418 - 969 WP_004151446.1 VirK/YbjX family protein -
DQG43_RS09745 1999575..2000228 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
DQG43_RS09750 2000225..2000416 - 192 WP_002911395.1 YebW family protein -
DQG43_RS09755 2000514..2000753 - 240 WP_002911393.1 YebV family protein -
DQG43_RS09760 2000869..2002302 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T107515 NZ_CP030296:1997724-1997826 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT107515 NZ_CP030296:c1997833-1997688 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References