Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2017431..2017702 Replicon chromosome
Accession NZ_CP030281
Organism Escherichia coli strain E308

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2017561..2017664 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2017431..2017702 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQW89_RS10620 2013986..2014648 - 663 WP_000944258.1 exodeoxyribonuclease X -
DQW89_RS10625 2014672..2015328 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
DQW89_RS10630 2015430..2015660 - 231 WP_000916763.1 DNA polymerase III subunit theta -
DQW89_RS10635 2015799..2016173 + 375 WP_000168747.1 CopC domain-containing protein YobA -
DQW89_RS10640 2016177..2017049 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
DQW89_RS10645 2017062..2017403 + 342 WP_000976472.1 YebY family protein -
- 2017431..2017702 - 272 - - Antitoxin
- 2017561..2017664 + 104 - - Toxin
DQW89_RS10650 2017799..2018455 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
DQW89_RS10655 2018456..2018647 - 192 WP_001338167.1 YebW family protein -
DQW89_RS10660 2018751..2018987 - 237 WP_001338166.1 DUF1480 family protein -
DQW89_RS10665 2019105..2020544 - 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T107454 NZ_CP030281:2017561-2017664 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT107454 NZ_CP030281:c2017702-2017431 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References