Detailed information of TA system TA107421

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 1304649..1305222
• Replicon: chromosome
• Accession: NZ_CP030265
• Organism: Skermanella pratensis strain W17

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DPR14_RS05975
• Protein ID: WP_158044331.1
• Coordinates: 1304649..1304936 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: DPR14_RS05980
• Protein ID: WP_158044332.1
• Coordinates: 1304923..1305222 (-)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DPR14_RS05955	1301628..1302383	+	756	WP_158044329.1	SOS response-associated peptidase	-
DPR14_RS05965	1303328..1304122	+	795	WP_158044330.1	hypothetical protein	-
DPR14_RS05975	1304649..1304936	-	288	WP_158044331.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DPR14_RS05980	1304923..1305222	-	300	WP_158044332.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
DPR14_RS05985	1305807..1307123	-	1317	WP_158044333.1	short-chain fatty acid transporter	-
DPR14_RS27200	1307646..1307822	-	177	WP_192499307.1	hypothetical protein	-
DPR14_RS05990	1307905..1308885	-	981	WP_158048008.1	2-hydroxyacid dehydrogenase	-
DPR14_RS05995	1309074..1309790	+	717	WP_211103935.1	RraA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-57)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10855.50 Da
• Isoelectric Point: 7.2008

>T107421 WP_158044331.1 NZ_CP030265:c1304936-1304649 [Skermanella pratensis]
VVVLEWRKTALADLLAIIDYISDDNLDAAQRLKNDIEAKTAKLPEHPKLYRTGRIAGTREMVVRTNYVVVYTEDTRAVTI
LRVLHAAQQWPPVQE

Nucleotide

• Length: 288 bp

>T107421 NZ_CP030265:c1304936-1304649 [Skermanella pratensis]
GTGGTGGTGCTTGAGTGGCGGAAGACGGCTCTCGCCGATCTCCTGGCAATCATCGATTACATATCAGATGACAATCTGGA
CGCCGCTCAGCGTCTGAAGAACGATATTGAGGCGAAGACTGCAAAGCTGCCTGAACATCCGAAGCTCTACCGGACCGGCC
GAATCGCCGGCACACGTGAAATGGTGGTTCGAACAAATTACGTGGTTGTCTATACCGAAGACACTCGCGCGGTGACGATC
CTTCGCGTGCTTCACGCCGCCCAACAATGGCCGCCAGTGCAGGAGTAG

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 10673.19 Da
• Isoelectric Point: 7.4035

>AT107421 WP_158044332.1 NZ_CP030265:c1305222-1304923 [Skermanella pratensis]
MAAQTSMLHIRVDDKLKADATEKLANVGLTVSDAVRILLTRISKEGALPAGLTTTPEAYDAWFRAKVHEALADTSPAAPH
QHVMDEAQALIDRKRRGGA

Nucleotide

• Length: 300 bp

>AT107421 NZ_CP030265:c1305222-1304923 [Skermanella pratensis]
ATGGCTGCCCAGACATCGATGCTGCACATCCGCGTGGACGACAAGCTCAAGGCTGACGCAACGGAAAAGCTCGCCAATGT
CGGCCTCACCGTCTCGGACGCCGTGCGCATCCTGCTCACGCGCATCTCCAAGGAAGGCGCTCTGCCGGCCGGATTGACGA
CAACGCCCGAAGCGTATGACGCATGGTTTCGGGCCAAGGTTCACGAGGCGCTGGCCGACACGAGCCCGGCGGCACCTCAT
CAGCATGTCATGGACGAAGCTCAAGCCTTGATCGACAGGAAACGCCGTGGTGGTGCTTGA