Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 723978..724569 Replicon chromosome
Accession NZ_CP030265
Organism Skermanella pratensis strain W17

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag DPR14_RS03295 Protein ID WP_211103995.1
Coordinates 724318..724569 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag DPR14_RS03290 Protein ID WP_211103994.1
Coordinates 723978..724295 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DPR14_RS03260 719346..719615 + 270 WP_192499244.1 SHOCT domain-containing protein -
DPR14_RS03265 719930..720715 + 786 WP_158043894.1 septum site-determining protein MinC -
DPR14_RS03270 720769..721584 + 816 WP_158043895.1 septum site-determining protein MinD -
DPR14_RS03275 721581..721889 + 309 WP_158043896.1 cell division topological specificity factor MinE -
DPR14_RS03280 722003..722857 - 855 WP_158043897.1 pantoate--beta-alanine ligase -
DPR14_RS03285 722850..723692 - 843 WP_158043898.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
DPR14_RS03290 723978..724295 - 318 WP_211103994.1 toxin-antitoxin system HicB family antitoxin Antitoxin
DPR14_RS03295 724318..724569 - 252 WP_211103995.1 type II toxin-antitoxin system HicA family toxin Toxin
DPR14_RS03300 724741..726108 + 1368 WP_158043900.1 CRTAC1 family protein -
DPR14_RS03305 726227..727225 + 999 WP_158043901.1 DUF1611 domain-containing protein -
DPR14_RS03310 727230..728231 + 1002 WP_158043902.1 dipeptide epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Uncharacterised protein family HicB

(52-102)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9286.76 Da        Isoelectric Point: 12.5736

>T107420 WP_211103995.1 NZ_CP030265:c724569-724318 [Skermanella pratensis]
MNNAHRRTLASIFDRPTRADIRWTAIEALVLALGGKVVERAGSRVLFEVSGITAIFHRPHPQPTTKKGAPPRRRARWMRS
GSS

Download         Length: 252 bp

>T107420 NZ_CP030265:c724569-724318 [Skermanella pratensis]
ATGAACAACGCGCACCGCAGGACACTGGCCAGCATCTTCGACCGGCCGACCAGAGCGGATATCCGCTGGACGGCGATCGA
GGCGCTTGTGCTGGCTCTGGGCGGCAAAGTCGTTGAGCGGGCTGGCAGCCGGGTGTTGTTCGAAGTGAGCGGCATAACCG
CGATCTTTCATCGGCCGCACCCGCAACCCACCACGAAGAAGGGCGCGCCACCACGAAGAAGGGCGCGGTGGATGCGGTCA
GGCAGTTCTTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11361.71 Da        Isoelectric Point: 4.6652

>AT107420 WP_211103994.1 NZ_CP030265:c724295-723978 [Skermanella pratensis]
MEYKGYVSGPIDFDPEDGTFSGTVAGLADVIHFQGSNSEELVQSFRGSIDEYLAYCEETGKAPDKPFSGKMLIRATPEIH
RKAAMRAQAEGKSLSAWVADTIKAA

Download         Length: 318 bp

>AT107420 NZ_CP030265:c724295-723978 [Skermanella pratensis]
ATGGAATACAAAGGGTATGTCTCAGGTCCCATCGACTTCGACCCGGAAGACGGCACGTTTTCCGGCACCGTAGCGGGCTT
GGCCGACGTGATCCATTTCCAGGGAAGCAATTCGGAGGAACTGGTTCAGAGCTTCCGCGGAAGCATTGATGAGTATCTCG
CCTATTGCGAAGAAACGGGCAAAGCCCCGGACAAGCCGTTCAGCGGCAAGATGCTGATCAGGGCGACCCCGGAAATACAC
CGGAAAGCGGCCATGCGGGCACAGGCCGAAGGCAAGAGCCTCAGCGCCTGGGTCGCCGACACCATCAAGGCCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References