Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 297698..298233 Replicon chromosome
Accession NZ_CP030265
Organism Skermanella pratensis strain W17

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DPR14_RS01335 Protein ID WP_158043556.1
Coordinates 297698..297973 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DPR14_RS01340 Protein ID WP_158043557.1
Coordinates 297973..298233 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DPR14_RS01315 293558..294157 - 600 WP_158043553.1 hypothetical protein -
DPR14_RS01320 294333..295760 + 1428 WP_158043554.1 threonine synthase -
DPR14_RS01325 295757..297019 + 1263 WP_158043555.1 insulinase family protein -
DPR14_RS01330 297068..297658 + 591 WP_158047932.1 GNAT family N-acetyltransferase -
DPR14_RS01335 297698..297973 - 276 WP_158043556.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DPR14_RS01340 297973..298233 - 261 WP_158043557.1 ribbon-helix-helix domain-containing protein Antitoxin
DPR14_RS01345 298363..299115 - 753 WP_158043558.1 tRNA pseudouridine(38-40) synthase TruA -
DPR14_RS01350 299112..300047 - 936 WP_158043559.1 methionyl-tRNA formyltransferase -
DPR14_RS01355 300069..300896 - 828 WP_192499219.1 class I SAM-dependent methyltransferase -
DPR14_RS01360 300899..301417 - 519 WP_158043561.1 peptide deformylase -
DPR14_RS01365 301506..302909 - 1404 WP_158043562.1 DNA recombination protein RmuC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10717.44 Da        Isoelectric Point: 10.7171

>T107419 WP_158043556.1 NZ_CP030265:c297973-297698 [Skermanella pratensis]
MELKWTGKALSDLSRLHDFLAPVNPQAAARVTRSLVSAPARLLEHPRIGEKLDEFNPREVRRLLVGRYEIRYEIRGSILY
VLRLWHVREDR

Download         Length: 276 bp

>T107419 NZ_CP030265:c297973-297698 [Skermanella pratensis]
ATGGAGCTGAAGTGGACCGGCAAGGCACTGTCGGATCTTTCGCGCCTTCATGATTTCCTCGCTCCCGTGAACCCGCAGGC
TGCCGCACGCGTGACCCGGTCGCTGGTATCCGCACCGGCGCGGTTGCTCGAACACCCACGTATCGGCGAGAAGCTGGATG
AGTTCAATCCCCGTGAGGTTCGCCGCCTTCTCGTGGGCCGCTACGAAATTCGGTACGAGATTCGAGGATCGATCCTCTAT
GTGCTCCGCCTCTGGCACGTGCGCGAGGATCGCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9668.93 Da        Isoelectric Point: 4.6112

>AT107419 WP_158043557.1 NZ_CP030265:c298233-297973 [Skermanella pratensis]
METKVLTAHVPLPLAEKVDQLAARLDRSHGWIVKQALSAWVEQEEERRRLTLEALADVDSGCVFDHQAVQAWADNLDTDS
PLPLPR

Download         Length: 261 bp

>AT107419 NZ_CP030265:c298233-297973 [Skermanella pratensis]
ATGGAAACCAAGGTATTGACCGCACACGTGCCGCTGCCGCTTGCCGAGAAAGTGGACCAGTTGGCTGCACGCTTGGATCG
CTCGCACGGTTGGATTGTCAAGCAAGCCCTGTCGGCCTGGGTCGAGCAAGAGGAAGAGCGTCGGCGCCTGACCCTCGAAG
CATTGGCCGACGTGGATTCCGGCTGTGTTTTCGACCATCAGGCCGTACAGGCGTGGGCCGATAACCTCGATACAGACTCA
CCGCTGCCGCTGCCCCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References