Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1250054..1250546 Replicon chromosome
Accession NZ_CP030241
Organism Moraxella bovis strain Epp63 (300)

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DQF64_RS06675 Protein ID WP_112742208.1
Coordinates 1250289..1250546 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DQF64_RS06670 Protein ID WP_208624093.1
Coordinates 1250054..1250299 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQF64_RS06645 1245157..1246206 + 1050 WP_112742206.1 RluA family pseudouridine synthase -
DQF64_RS06650 1246325..1247122 + 798 WP_112742207.1 polyphenol oxidase family protein -
DQF64_RS06655 1247119..1247839 + 721 Protein_1296 bestrophin family protein -
DQF64_RS06660 1247936..1249301 + 1366 Protein_1297 DUF853 family protein -
DQF64_RS06665 1249479..1249766 + 288 WP_078273310.1 DUF1315 family protein -
DQF64_RS14995 1249848..1250012 - 165 WP_162860378.1 hypothetical protein -
DQF64_RS06670 1250054..1250299 + 246 WP_208624093.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DQF64_RS06675 1250289..1250546 + 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
DQF64_RS06680 1250605..1251114 + 510 WP_112742209.1 peptidyl-prolyl cis-trans isomerase -
DQF64_RS06685 1251180..1251983 + 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
DQF64_RS06690 1252079..1254601 - 2523 WP_112742210.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-69)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T107410 WP_112742208.1 NZ_CP030241:1250289-1250546 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T107410 NZ_CP030241:1250289-1250546 [Moraxella bovis]
TTGAGGATTAGATGGTTTGATGAGGTATGGGAGGATTATTTGTATTGGCAAAGCCAAGATAAGAAAACCATAAAACGTAT
TAATACCTTGATTAAGGATTGCAGACGAGACCCTTTTGACGGTATCGGCAAACCCGAACCATTAAAATATAACCTAACAG
GCTACTGGTTAAGACGCATTGATGATGCCAACCGCTTGGTTTATTGTTGCGAAAGTGAAACACTCATCATTTCATGCCGT
CATCATTATGAGGCTTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9233.36 Da        Isoelectric Point: 6.2120

>AT107410 WP_208624093.1 NZ_CP030241:1250054-1250299 [Moraxella bovis]
VMNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIE
D

Download         Length: 246 bp

>AT107410 NZ_CP030241:1250054-1250299 [Moraxella bovis]
GTGATGAATTATAGCGAATTTCGCCAAAACCTAGCGTCCGCCCTTGATTATGTTCAAGACAGCCATGCCCCTGTGATTGT
CAAACGTGGCAAACATTCTGCGGTGGTGATTAGTCTTGATGAATATAATGCTTTTAAAGAAACAGATTATCTATTGTCAA
ACCCTGCTAATGCCGAACACCTTATGCGTGGCGTGCAAGCGGTAAAAAATCGTCAACTTACCCAAAGGGATTTGATTGAG
GATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References