Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 816617..817194 Replicon chromosome
Accession NZ_CP030241
Organism Moraxella bovis strain Epp63 (300)

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DQF64_RS04300 Protein ID WP_078275234.1
Coordinates 816859..817194 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DQF64_RS04295 Protein ID WP_078275235.1
Coordinates 816617..816859 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQF64_RS04270 812516..812938 - 423 WP_078275239.1 hypothetical protein -
DQF64_RS04275 812947..813252 - 306 WP_078275238.1 hypothetical protein -
DQF64_RS04280 813412..814038 - 627 WP_078275237.1 septation protein IspZ -
DQF64_RS04285 814227..814949 + 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
DQF64_RS04290 815331..816410 - 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
DQF64_RS04295 816617..816859 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DQF64_RS04300 816859..817194 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQF64_RS04305 817256..818251 + 996 WP_208624081.1 polyprenyl synthetase family protein -
DQF64_RS04310 818323..818511 + 189 WP_143821748.1 hypothetical protein -
DQF64_RS04315 818601..820745 - 2145 WP_112741953.1 cation-translocating P-type ATPase -
DQF64_RS04320 820910..821494 - 585 WP_112741954.1 hypothetical protein -
DQF64_RS04325 821654..821854 - 201 WP_112741955.1 hypothetical protein -
DQF64_RS04330 821832..822011 - 180 WP_112741956.1 BrnT family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T107407 WP_078275234.1 NZ_CP030241:816859-817194 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T107407 NZ_CP030241:816859-817194 [Moraxella bovis]
ATGTGCGAATTAATGTATGAATTAGAATTTGACGAGCGAGCCTTAAAAGAATGGCAAAAACTGGGCGACACCATAAAAAC
GCAGTTTAAAAAGAGACTGGCTAAGGTGCTAAAAAATCCGCACATCATCGCCAATCGCCTAAGCGGTGGACAAAATTTAT
ACAAAATCAACTTCCGCTCGGCAGGTTATCGCCTTGTGTATCAAGTTGAAGATGATAAAGTGGTGGTGTTTGTCATCGTG
ATGGGTAAGCGTGAGAAAAATGCCGTCTATGACACCGCCGAAGAATGGCTTGCTGAACGTCAATCGGACAATCAAGACAC
ACAATCTGTCAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT107407 WP_078275235.1 NZ_CP030241:816617-816859 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT107407 NZ_CP030241:816617-816859 [Moraxella bovis]
ATGGCAAATATCGTGGCTCGTGTGGACGATGACCTAAAAGCCCAATCATTTTTGGTACTGCAAGAACTTGGCGTGACACC
GTCTGAGCTTATCCGCCAAACCTTGCAATATGTGGCTTATCACAAAAAATTACCCTTTAAGACGGTGGTTTTGACCGATG
AAGACAGTGAGCTTTTAGCCCTTGCCAAAGAACGCCTTGATAATCCTGCCCCACGCATCAAAGTCAGTTTGGACGAGCTT
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References