Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 712999..713648 Replicon chromosome
Accession NZ_CP030241
Organism Moraxella bovis strain Epp63 (300)

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DQF64_RS03675 Protein ID WP_078274052.1
Coordinates 713247..713648 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DQF64_RS03670 Protein ID WP_112741908.1
Coordinates 712999..713232 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQF64_RS03650 708395..708844 - 450 WP_078274056.1 cytochrome c -
DQF64_RS03655 709026..710018 - 993 WP_078274055.1 oxygen-dependent coproporphyrinogen oxidase -
DQF64_RS03660 710038..710631 - 594 WP_208624078.1 GTP cyclohydrolase II -
DQF64_RS03665 710852..712951 + 2100 WP_078274054.1 1-deoxy-D-xylulose-5-phosphate synthase -
DQF64_RS03670 712999..713232 + 234 WP_112741908.1 antitoxin Antitoxin
DQF64_RS03675 713247..713648 + 402 WP_078274052.1 type II toxin-antitoxin system VapC family toxin Toxin
DQF64_RS03680 714172..714672 + 501 WP_112741909.1 WG repeat-containing protein -
DQF64_RS03685 714794..715624 + 831 WP_078274050.1 inositol monophosphatase -
DQF64_RS03690 715723..716412 - 690 WP_078274049.1 SIMPL domain-containing protein -
DQF64_RS03705 717148..717567 - 420 WP_078274047.1 RNA-binding protein -
DQF64_RS03710 717564..717713 - 150 WP_162860355.1 hypothetical protein -
DQF64_RS03715 717759..717992 - 234 WP_112741910.1 ASCH domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(8-54)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15131.33 Da        Isoelectric Point: 6.8510

>T107406 WP_078274052.1 NZ_CP030241:713247-713648 [Moraxella bovis]
MFSFMLDTNIYIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI

Download         Length: 402 bp

>T107406 NZ_CP030241:713247-713648 [Moraxella bovis]
ATGTTTAGTTTTATGCTGGATACCAATATCTACATTTATGTGATAAAAGAACGCCCCATAAAAGCATTAAACAAATTTAA
CCAATATGCAGGGCGGATTTGCGTAAGCAGTATCGTGGCAAGCGAGTTGTATTTTGGGGCGTACAACAGCCAATTTATGG
ATAAAAATCTACATCAAGTCGAAGATTTTTTATCACGTTTGACGGTGCTTGATTATACCGCAGAATGCTCGCCCCATTAC
GGCGAGATTTGTGCTGATTTGACCAAGCAGGGCAAGCTCATTAGTGAAAATGACATTCATATCGCCTCTCATGCACGGGC
ATTGGGGCTGACCTTGATTACCAATAATACCGATGAATTTAAACGAGTGTCAGGGCTTAGGATTGGTAATTGGGCGATTT
GA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8990.22 Da        Isoelectric Point: 6.2884

>AT107406 WP_112741908.1 NZ_CP030241:712999-713232 [Moraxella bovis]
MQTSVFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKSERLTFD

Download         Length: 234 bp

>AT107406 NZ_CP030241:712999-713232 [Moraxella bovis]
ATGCAAACCAGTGTTTTTTTTAATAATCGCACCCAAGCGGTTCGCATTCCTGCCAAATTTCGCTTTGATGACGATGTCAA
AGCCGTCATGATTAGAAAAGTGGGCAATGAGCGGATTTTGACCCCAATTGATGGTGTGTGGGACAGCTTTTTTTTGAGTG
ATGAGCGAGCGAGTGATGATTTTATGGCAAACCGCCCGACCATGCCAAAAAGCGAGCGATTGACTTTTGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References