Detailed information of TA system TA107358

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/RelE-RHH
• Location: 1985..2532
• Replicon: plasmid pSA20101045.1
• Accession: NZ_CP030234
• Organism: Salmonella enterica strain SA20101045

Toxin (Protein)

• Gene name: parE
• Uniprot ID: A0A896ZGX1
• Locus tag: CHE40_RS24100
• Protein ID: WP_000969997.1
• Coordinates: 2251..2532 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: E0WH52
• Locus tag: CHE40_RS24095
• Protein ID: WP_000079932.1
• Coordinates: 1985..2254 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHE40_RS24080	46..1077	+	1032	WP_001690254.1	replication initiation protein	-
CHE40_RS24095	1985..2254	+	270	WP_000079932.1	hypothetical protein	Antitoxin
CHE40_RS24100	2251..2532	+	282	WP_000969997.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CHE40_RS24105	2728..3069	-	342	WP_000578011.1	hypothetical protein	-
CHE40_RS24110	3369..3956	+	588	WP_024189984.1	serine acetyltransferase	-
CHE40_RS24115	4238..4831	-	594	WP_000517696.1	hypothetical protein	-
CHE40_RS24125	5185..6531	+	1347	WP_032082920.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..94810	94810

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-112)

Antitoxin

• Antitoxin CbeA (18-117)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 12066.38 Da
• Isoelectric Point: 12.7685

>T107358 WP_000969997.1 NZ_CP030234:2251-2532 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Nucleotide

• Length: 282 bp

>T107358 NZ_CP030234:2251-2532 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 11553.68 Da
• Isoelectric Point: 12.7493

>AT107358 WP_000079932.1 NZ_CP030234:1985-2254 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKK

Nucleotide

• Length: 270 bp

>AT107358 NZ_CP030234:1985-2254 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Structures

Toxin

• AlphaFold DB: A0A896ZGX1

Antitoxin

• AlphaFold DB: A0A5U8RN22