Detailed information of TA system TA107357

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 42109..42644
• Replicon: plasmid pSA20021456.3
• Accession: NZ_CP030222
• Organism: Salmonella enterica strain SA20021456

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CHC34_RS27680
• Protein ID: WP_154808191.1
• Coordinates: 42109..42396 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CHC34_RS27685
• Protein ID: WP_154808192.1
• Coordinates: 42393..42644 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHC34_RS27650	37527..38444	-	918	WP_116779492.1	DNA-binding protein	-
CHC34_RS27655	39058..39822	+	765	WP_116779491.1	tyrosine-type recombinase/integrase	-
CHC34_RS27660	39936..40601	+	666	WP_116779490.1	peptidyl-arginine deiminase	-
CHC34_RS27665	40641..40961	+	321	WP_116779489.1	hypothetical protein	-
CHC34_RS27670	41464..41718	-	255	WP_154808195.1	hypothetical protein	-
CHC34_RS27675	41874..42104	-	231	WP_154808190.1	hypothetical protein	-
CHC34_RS27680	42109..42396	-	288	WP_154808191.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CHC34_RS27685	42393..42644	-	252	WP_154808192.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CHC34_RS27690	42769..43059	-	291	WP_154808193.1	hypothetical protein	-
CHC34_RS27695	43109..43537	-	429	WP_023233714.1	hypothetical protein	-
CHC34_RS27700	43597..43884	-	288	WP_023233715.1	hypothetical protein	-
CHC34_RS27705	44383..44874	+	492	WP_023233716.1	hypothetical protein	-
CHC34_RS27710	44931..45386	+	456	WP_001287806.1	hypothetical protein	-
CHC34_RS27715	45736..45987	+	252	WP_000213776.1	hypothetical protein	-
CHC34_RS27720	46026..46724	+	699	WP_015062745.1	lytic transglycosylase domain-containing protein	-
CHC34_RS27725	46699..47052	+	354	WP_023233717.1	hypothetical protein	-
CHC34_RS27730	47052..47423	+	372	WP_015062746.1	VirB3 family type IV secretion system protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..54448	54448

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Haemolysin expression modulating, HHA (13-69)

Antitoxin

• Biofilm formation regulator YbaJ (1-117)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 14146.97 Da
• Isoelectric Point: 5.5500

>T107357 WP_154808191.1 NZ_CP030222:c42396-42109 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFF

Nucleotide

• Length: 288 bp

>T107357 NZ_CP030222:c42396-42109 [Salmonella enterica]
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Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 12380.85 Da
• Isoelectric Point: 5.5500

>AT107357 WP_154808192.1 NZ_CP030222:c42644-42393 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Nucleotide

• Length: 252 bp

>AT107357 NZ_CP030222:c42644-42393 [Salmonella enterica]
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