Detailed information of TA system TA107355

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 138423..138948
• Replicon: plasmid pSA20021456.1
• Accession: NZ_CP030220
• Organism: Salmonella enterica strain SA20021456

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: I3VZQ7
• Locus tag: CHC34_RS26955
• Protein ID: WP_001159874.1
• Coordinates: 138423..138728 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: -
• Locus tag: CHC34_RS26960
• Protein ID: WP_154808150.1
• Coordinates: 138730..138948 (-)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHC34_RS26935	136119..136820	+	702	WP_196214741.1	replication initiation protein	-
CHC34_RS26940	136902..137690	-	789	WP_154808147.1	site-specific integrase	-
CHC34_RS26945	137725..137985	-	261	WP_154808148.1	hypothetical protein	-
CHC34_RS26950	138131..138421	-	291	WP_154808149.1	cytoplasmic protein	-
CHC34_RS26955	138423..138728	-	306	WP_001159874.1	type II toxin-antitoxin system toxin CcdB	Toxin
CHC34_RS26960	138730..138948	-	219	WP_154808150.1	type II toxin-antitoxin system antitoxin CcdA	Antitoxin
CHC34_RS26965	139651..140271	+	621	WP_154808151.1	DNA-binding protein	-
CHC34_RS26970	140337..142433	-	2097	WP_023221723.1	peptidase domain-containing ABC transporter	-
CHC34_RS26975	142426..143613	-	1188	WP_023221724.1	HlyD family secretion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..159279	159279

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 15030.03 Da
• Isoelectric Point: 5.5500

>T107355 WP_001159874.1 NZ_CP030220:c138728-138423 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 306 bp

>T107355 NZ_CP030220:c138728-138423 [Salmonella enterica]
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Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 10761.91 Da
• Isoelectric Point: 5.5500

>AT107355 WP_154808150.1 NZ_CP030220:c138948-138730 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 219 bp

>AT107355 NZ_CP030220:c138948-138730 [Salmonella enterica]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Structures

Toxin

• AlphaFold DB: A0A600Z065