Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 40755..41277 Replicon plasmid pSA19992307.1
Accession NZ_CP030208
Organism Salmonella enterica strain SA19992307

Toxin (Protein)


Gene name relE Uniprot ID G3CAN5
Locus tag CHC30_RS25200 Protein ID WP_000220560.1
Coordinates 40996..41277 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G3CAG1
Locus tag CHC30_RS25195 Protein ID WP_000121743.1
Coordinates 40755..41006 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHC30_RS25155 36166..36786 + 621 WP_000864788.1 ParA family protein -
CHC30_RS25160 36838..37068 + 231 WP_000051066.1 partitioning protein -
CHC30_RS25175 37707..38129 - 423 WP_000202949.1 hypothetical protein -
CHC30_RS25180 38197..38643 - 447 WP_001074381.1 hypothetical protein -
CHC30_RS25185 38683..39519 - 837 WP_001575533.1 replication initiation protein -
CHC30_RS25195 40755..41006 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin
CHC30_RS25200 40996..41277 + 282 WP_000220560.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CHC30_RS25205 41423..41746 + 324 WP_001181909.1 hypothetical protein -
CHC30_RS25210 41791..42036 + 246 WP_000356542.1 hypothetical protein -
CHC30_RS25215 42026..42241 + 216 WP_001180117.1 hypothetical protein -
CHC30_RS25220 42334..42663 + 330 WP_000866650.1 hypothetical protein -
CHC30_RS25225 42706..42885 + 180 WP_001575529.1 hypothetical protein -
CHC30_RS25230 42907..43104 + 198 WP_001675595.1 hypothetical protein -
CHC30_RS25235 43117..43389 + 273 WP_000160399.1 hypothetical protein -
CHC30_RS25650 43646..43720 + 75 Protein_60 DNA distortion polypeptide 3 -
CHC30_RS25245 43715..44260 + 546 WP_000757691.1 hypothetical protein -
CHC30_RS25250 44263..45444 + 1182 WP_000539536.1 relaxase/mobilization nuclease domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..74577 74577


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T107349 WP_000220560.1 NZ_CP030208:40996-41277 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T107349 NZ_CP030208:40996-41277 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 10784.64 Da        Isoelectric Point: 12.7191

>AT107349 WP_000121743.1 NZ_CP030208:40755-41006 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Download         Length: 252 bp

>AT107349 NZ_CP030208:40755-41006 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB G3CAN5

Antitoxin

Source ID Structure
AlphaFold DB A0A3S5I301

References