Detailed information of TA system TA107346

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vagCD/VapC-VagC
• Location: 13588..14237
• Replicon: plasmid pSA20083530.3
• Accession: NZ_CP030206
• Organism: Salmonella enterica strain SA20083530

Toxin (Protein)

• Gene name: vagD
• Uniprot ID: -
• Locus tag: CHD70_RS27885
• Protein ID: WP_114047719.1
• Coordinates: 13588..14007 (-)
• Length: 140 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: -
• Locus tag: CHD70_RS27890
• Protein ID: WP_114047720.1
• Coordinates: 14004..14237 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHD70_RS27850	9614..9844	-	231	WP_114047716.1	hypothetical protein	-
CHD70_RS27855	9976..10509	+	534	WP_114047731.1	hypothetical protein	-
CHD70_RS27860	10512..10964	+	453	WP_029403594.1	hypothetical protein	-
CHD70_RS27865	10964..11545	+	582	WP_114047717.1	hypothetical protein	-
CHD70_RS27870	11591..11944	-	354	WP_114047718.1	hypothetical protein	-
CHD70_RS27875	12159..12305	-	147	WP_083264764.1	type I toxin-antitoxin system Hok family toxin	-
CHD70_RS27880	12546..12893	-	348	WP_070133931.1	hypothetical protein	-
CHD70_RS27885	13588..14007	-	420	WP_114047719.1	type II toxin-antitoxin system VapC family toxin	Toxin
CHD70_RS27890	14004..14237	-	234	WP_114047720.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
CHD70_RS27895	14705..15367	+	663	WP_036944392.1	plasmid stability/partitioning protein	-
CHD70_RS27900	15443..15721	+	279	WP_029403588.1	hypothetical protein	-
CHD70_RS27905	15874..16185	+	312	WP_205318807.1	CcgAII protein	-
CHD70_RS27910	16406..16600	+	195	WP_114047721.1	hypothetical protein	-
CHD70_RS27915	17489..18325	-	837	WP_114047733.1	replication initiation protein	-
CHD70_RS27925	18655..19083	-	429	WP_070133934.1	type II toxin-antitoxin system VapC family toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..27709	27709

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (5-59)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 140 a.a.
• Molecular weight: 20622.74 Da
• Isoelectric Point: 5.5500

>T107346 WP_114047719.1 NZ_CP030206:c14007-13588 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 420 bp

>T107346 NZ_CP030206:c14007-13588 [Salmonella enterica]
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Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 11497.79 Da
• Isoelectric Point: 5.5500

>AT107346 WP_114047720.1 NZ_CP030206:c14237-14004 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 234 bp

>AT107346 NZ_CP030206:c14237-14004 [Salmonella enterica]
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