Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 16388..17031 Replicon plasmid pSA20051401.2
Accession NZ_CP030198
Organism Salmonella enterica strain SA20051401

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag CHD15_RS26000 Protein ID WP_114064535.1
Coordinates 16615..17031 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag CHD15_RS25995 Protein ID WP_114064534.1
Coordinates 16388..16618 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHD15_RS27090 11611..11763 + 153 WP_001838496.1 hypothetical protein -
CHD15_RS25965 12376..13070 - 695 Protein_10 CPBP family intramembrane metalloprotease -
CHD15_RS25970 13574..14351 - 778 Protein_11 phage integrase family protein -
CHD15_RS25975 14386..14830 - 445 Protein_12 hypothetical protein -
CHD15_RS25980 14827..15117 - 291 WP_114064532.1 cytoplasmic protein -
CHD15_RS25985 15119..15424 - 306 WP_114064533.1 type II toxin-antitoxin system toxin CcdB -
CHD15_RS25990 15426..15644 - 219 WP_031570335.1 type II toxin-antitoxin system antitoxin CcdA -
CHD15_RS25995 16388..16618 + 231 WP_114064534.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CHD15_RS26000 16615..17031 + 417 WP_114064535.1 type II toxin-antitoxin system VapC family toxin Toxin
CHD15_RS26005 17247..17428 - 182 Protein_18 hypothetical protein -
CHD15_RS26015 18000..19019 + 1020 WP_114064537.1 hypothetical protein -
CHD15_RS26020 19356..19676 + 321 WP_114064538.1 hypothetical protein -
CHD15_RS26025 19808..20710 + 903 WP_114064539.1 hypothetical protein -
CHD15_RS26920 21095..21697 - 603 WP_162785958.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..134274 134274


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 17834.22 Da        Isoelectric Point: 12.9398

>T107342 WP_114064535.1 NZ_CP030198:16615-17031 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 417 bp

>T107342 NZ_CP030198:16615-17031 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 9887.42 Da        Isoelectric Point: 12.6808

>AT107342 WP_114064534.1 NZ_CP030198:16388-16618 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 231 bp

>AT107342 NZ_CP030198:16388-16618 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References