Detailed information of TA system TA107340

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vagCD/VapC-VagC
• Location: 71001..71644
• Replicon: plasmid pSA20051401.1
• Accession: NZ_CP030197
• Organism: Salmonella enterica strain SA20051401

Toxin (Protein)

• Gene name: vagD
• Uniprot ID: -
• Locus tag: CHD15_RS25490
• Protein ID: WP_065807752.1
• Coordinates: 71001..71417 (-)
• Length: 139 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: -
• Locus tag: CHD15_RS25495
• Protein ID: WP_114064496.1
• Coordinates: 71414..71644 (-)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHD15_RS25465	66555..67244	-	690	WP_114064494.1	helix-turn-helix domain-containing protein	-
CHD15_RS25470	67400..67567	-	168	Protein_70	helix-turn-helix domain-containing protein	-
CHD15_RS25475	68002..69024	-	1023	WP_114064526.1	adenylate/guanylate cyclase domain-containing protein	-
CHD15_RS25480	69378..69911	-	534	WP_097308023.1	hypothetical protein	-
CHD15_RS25485	70226..70969	-	744	WP_114064495.1	hypothetical protein	-
CHD15_RS25490	71001..71417	-	417	WP_065807752.1	type II toxin-antitoxin system VapC family toxin	Toxin
CHD15_RS25495	71414..71644	-	231	WP_114064496.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
CHD15_RS25505	72193..73155	+	963	WP_114064497.1	hypothetical protein	-
CHD15_RS25510	73156..73446	+	291	WP_094965528.1	cytoplasmic protein	-
CHD15_RS27075	73443..73976	+	534	Protein_78	cytoplasmic protein	-
CHD15_RS25520	73989..74771	+	783	WP_058108850.1	site-specific integrase	-
CHD15_RS25525	74986..75849	-	864	WP_000074442.1	RepB family plasmid replication initiator protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..141502	141502

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (5-60)

Antitoxin

• HicB-like antitoxin of toxin-antitoxin system (10-104)

Sequences

Toxin

Protein

• Length: 139 a.a.
• Molecular weight: 20475.56 Da
• Isoelectric Point: 5.5500

>T107340 WP_065807752.1 NZ_CP030197:c71417-71001 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 417 bp

>T107340 NZ_CP030197:c71417-71001 [Salmonella enterica]
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Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 11350.61 Da
• Isoelectric Point: 5.5500

>AT107340 WP_114064496.1 NZ_CP030197:c71644-71414 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 231 bp

>AT107340 NZ_CP030197:c71644-71414 [Salmonella enterica]
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