Detailed information of TA system TA107339

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hicAB/-
• Location: 34781..35373
• Replicon: plasmid pSA20080453.1
• Accession: NZ_CP030195
• Organism: Salmonella enterica strain SA20080453

Toxin (Protein)

• Gene name: hicA
• Uniprot ID: -
• Locus tag: CHD54_RS23005
• Protein ID: WP_071645784.1
• Coordinates: 35125..35373 (-)
• Length: 83 a.a.

Antitoxin (Protein)

• Gene name: hicB
• Uniprot ID: -
• Locus tag: CHD54_RS23000
• Protein ID: WP_071645785.1
• Coordinates: 34781..35128 (-)
• Length: 116 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHD54_RS22970	30741..31037	-	297	WP_071645790.1	TrbC/VirB2 family protein	-
CHD54_RS22975	31015..31665	-	651	WP_071678421.1	lytic transglycosylase domain-containing protein	-
CHD54_RS22980	31698..31910	-	213	WP_071645788.1	hypothetical protein	-
CHD54_RS22985	31873..32355	-	483	WP_071645787.1	transcription termination factor NusG	-
CHD54_RS22990	32708..33874	-	1167	WP_071678439.1	relaxase/mobilization nuclease domain-containing protein	-
CHD54_RS22995	33877..34422	-	546	WP_071645786.1	DNA distortion polypeptide 1	-
CHD54_RS23365	34417..34491	-	75	Protein_43	DNA distortion polypeptide 3	-
CHD54_RS23000	34781..35128	-	348	WP_071645785.1	type II toxin-antitoxin system HicB family antitoxin	Antitoxin
CHD54_RS23005	35125..35373	-	249	WP_071645784.1	type II toxin-antitoxin system HicA family toxin	Toxin
CHD54_RS23010	35523..35795	-	273	WP_071645783.1	hypothetical protein	-
CHD54_RS23260	35808..35957	-	150	WP_167668528.1	hypothetical protein	-
CHD54_RS23015	36028..36207	-	180	WP_071645782.1	hypothetical protein	-
CHD54_RS23020	36250..36579	-	330	WP_071678420.1	hypothetical protein	-
CHD54_RS23025	36671..36886	-	216	WP_001180117.1	hypothetical protein	-
CHD54_RS23030	36876..37121	-	246	WP_134954084.1	hypothetical protein	-
CHD54_RS23035	37166..37489	-	324	WP_134954085.1	hypothetical protein	-
CHD54_RS23040	37635..37916	-	282	WP_134954086.1	type II toxin-antitoxin system RelE/ParE family toxin	-
CHD54_RS23045	37906..38157	-	252	WP_000121743.1	plasmid stabilization protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..38923	38923

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (10-113)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 83 a.a.
• Molecular weight: 12233.67 Da
• Isoelectric Point: 5.5500

>T107339 WP_071645784.1 NZ_CP030195:c35373-35125 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFF

Nucleotide

• Length: 249 bp

>T107339 NZ_CP030195:c35373-35125 [Salmonella enterica]
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Antitoxin

Protein

• Length: 116 a.a.
• Molecular weight: 17090.50 Da
• Isoelectric Point: 5.5500

>AT107339 WP_071645785.1 NZ_CP030195:c35128-34781 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 348 bp

>AT107339 NZ_CP030195:c35128-34781 [Salmonella enterica]
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