Detailed information of TA system TA107336

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vagCD/VapC-VagC
• Location: 61187..61842
• Replicon: plasmid pIncFII.2
• Accession: NZ_CP030177
• Organism: Salmonella enterica subsp. enterica serovar Milwaukee str. SA19950795

Toxin (Protein)

• Gene name: vagD
• Uniprot ID: -
• Locus tag: LFZ28_RS25930
• Protein ID: WP_058108470.1
• Coordinates: 61187..61615 (-)
• Length: 143 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: -
• Locus tag: LFZ28_RS25935
• Protein ID: WP_058108471.1
• Coordinates: 61612..61842 (-)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LFZ28_RS26465	56511..57104	+	594	WP_162802315.1	hypothetical protein	-
LFZ28_RS25905	57544..58563	-	1020	WP_114159194.1	hypothetical protein	-
LFZ28_RS25915	59473..60204	-	732	WP_058108469.1	type III secretion system effector phosphothreonine lyase	-
LFZ28_RS25920	60279..60527	-	249	Protein_64	hypothetical protein	-
LFZ28_RS25930	61187..61615	-	429	WP_058108470.1	type II toxin-antitoxin system VapC family toxin	Toxin
LFZ28_RS25935	61612..61842	-	231	WP_058108471.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
LFZ28_RS25945	62388..63350	+	963	WP_058108472.1	hypothetical protein	-
LFZ28_RS25950	63351..63641	+	291	WP_058108851.1	hypothetical protein	-
LFZ28_RS25955	63638..64137	+	500	Protein_69	cytoplasmic protein	-
LFZ28_RS25960	64134..64916	+	783	WP_058108850.1	site-specific integrase	-
LFZ28_RS25965	65131..65994	-	864	WP_000074442.1	RepB family plasmid replication initiator protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..131435	131435

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-132)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 143 a.a.
• Molecular weight: 21064.27 Da
• Isoelectric Point: 5.5500

>T107336 WP_058108470.1 NZ_CP030177:c61615-61187 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 429 bp

>T107336 NZ_CP030177:c61615-61187 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
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Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 11350.61 Da
• Isoelectric Point: 5.5500

>AT107336 WP_058108471.1 NZ_CP030177:c61842-61612 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 231 bp

>AT107336 NZ_CP030177:c61842-61612 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
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