Detailed information of TA system TA107334

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 139154..139779
• Replicon: plasmid pIncFII.1
• Accession: NZ_CP030176
• Organism: Salmonella enterica subsp. enterica serovar Milwaukee str. SA19950795

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: LFZ28_RS25515
• Protein ID: WP_058108422.1
• Coordinates: 139154..139552 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A8F2UQ48
• Locus tag: LFZ28_RS25520
• Protein ID: WP_000450263.1
• Coordinates: 139552..139779 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LFZ28_RS25500	135048..135530	+	483	WP_000787664.1	hypothetical protein	-
LFZ28_RS25505	135776..136507	+	732	WP_058108420.1	complement resistance protein TraT	-
LFZ28_RS25510	136884..139145	+	2262	WP_058108421.1	type IV conjugative transfer system coupling protein TraD	-
LFZ28_RS25515	139154..139552	-	399	WP_058108422.1	tRNA(fMet)-specific endonuclease VapC	Toxin
LFZ28_RS25520	139552..139779	-	228	WP_000450263.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..148530	148530

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (40-268)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (10-51)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T107334 WP_058108422.1 NZ_CP030176:c139552-139154 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T107334 NZ_CP030176:c139552-139154 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT107334 WP_000450263.1 NZ_CP030176:c139779-139552 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT107334 NZ_CP030176:c139779-139552 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
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