Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3489346..3489491 Replicon chromosome
Accession NZ_CP030174
Organism Klebsiella pneumoniae subsp. pneumoniae strain 11219

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3489353..3489455 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3489346..3489491 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQB71_RS17790 3484878..3486311 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DQB71_RS17795 3486427..3486666 + 240 WP_002911393.1 YebV family protein -
DQB71_RS17800 3486764..3486955 + 192 WP_002911395.1 YebW family protein -
DQB71_RS17805 3486952..3487605 - 654 WP_020802220.1 protein-serine/threonine phosphatase -
DQB71_RS17810 3487762..3488730 + 969 WP_004151446.1 VirK/YbjX family protein -
DQB71_RS27440 3488835..3488978 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3489346..3489491 + 146 - - Antitoxin
- 3489353..3489455 - 103 - - Toxin
DQB71_RS17820 3489614..3489952 - 339 WP_002911404.1 YebY family protein -
DQB71_RS17825 3489969..3490838 - 870 WP_112162692.1 copper homeostasis membrane protein CopD -
DQB71_RS17830 3490842..3491216 - 375 WP_112162694.1 CopC domain-containing protein YobA -
DQB71_RS17835 3491329..3491559 + 231 WP_002911406.1 DNA polymerase III subunit theta -
DQB71_RS17840 3491638..3492297 + 660 WP_002911407.1 exodeoxyribonuclease X -
DQB71_RS17845 3492301..3494361 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T107320 NZ_CP030174:c3489455-3489353 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT107320 NZ_CP030174:3489346-3489491 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References