Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1881665..1881810 Replicon chromosome
Accession NZ_CP030172
Organism Klebsiella pneumoniae subsp. pneumoniae strain 12208

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1881701..1881803 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1881665..1881810 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQB68_RS09295 1876795..1878855 + 2061 WP_004151449.1 oligopeptidase B -
DQB68_RS09300 1878859..1879518 - 660 WP_021440386.1 exodeoxyribonuclease X -
DQB68_RS09305 1879597..1879827 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DQB68_RS09310 1879940..1880314 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DQB68_RS09315 1880318..1881187 + 870 WP_021440385.1 copper homeostasis membrane protein CopD -
DQB68_RS09320 1881204..1881542 + 339 WP_002911404.1 YebY family protein -
- 1881665..1881810 - 146 - - Antitoxin
- 1881701..1881803 + 103 - - Toxin
DQB68_RS26205 1882179..1882322 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DQB68_RS09330 1882427..1883395 - 969 WP_014907334.1 VirK/YbjX family protein -
DQB68_RS09335 1883552..1884205 + 654 WP_021440384.1 protein-serine/threonine phosphatase -
DQB68_RS09340 1884202..1884393 - 192 WP_002911395.1 YebW family protein -
DQB68_RS09345 1884491..1884730 - 240 WP_002911393.1 YebV family protein -
DQB68_RS09350 1884846..1886279 - 1434 WP_021440382.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T107278 NZ_CP030172:1881701-1881803 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT107278 NZ_CP030172:c1881810-1881665 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References