Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 33460..34013 Replicon plasmid unnamed
Accession NZ_CP030165
Organism Xanthomonas citri pv. punicae strain LMG7439

Toxin (Protein)


Gene name relE Uniprot ID A0A6M2VVM8
Locus tag XapA_RS23280 Protein ID WP_033480619.1
Coordinates 33460..33753 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6M2VW75
Locus tag XapA_RS23285 Protein ID WP_005933973.1
Coordinates 33741..34013 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XapA_RS23245 28921..29976 + 1056 WP_174854928.1 DNA-binding protein -
XapA_RS23250 30218..31396 + 1179 WP_005934659.1 avirulence B domain protein -
XapA_RS23255 31544..31780 - 237 Protein_32 transposase -
XapA_RS23265 32014..32511 + 498 Protein_33 Tn3 family transposase -
XapA_RS23270 32529..33225 + 697 Protein_34 UPF0149 family protein -
XapA_RS23275 33269..33460 - 192 WP_033480620.1 hypothetical protein -
XapA_RS23280 33460..33753 - 294 WP_033480619.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XapA_RS23285 33741..34013 - 273 WP_005933973.1 CopG family ribbon-helix-helix protein Antitoxin
XapA_RS23290 34091..35767 - 1677 WP_005933971.1 relaxase/mobilization nuclease domain-containing protein -
XapA_RS23295 35764..36072 - 309 WP_005933969.1 hypothetical protein -
XapA_RS23300 36358..36648 + 291 WP_033480618.1 hypothetical protein -
XapA_RS23305 36645..36947 + 303 WP_033480617.1 hypothetical protein -
XapA_RS23315 37457..37825 + 369 WP_005933960.1 hypothetical protein -
XapA_RS23320 37857..38786 - 930 WP_005933956.1 DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..157583 157583


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10992.44 Da        Isoelectric Point: 6.2258

>T107260 WP_033480619.1 NZ_CP030165:c33753-33460 [Xanthomonas citri pv. punicae]
VPHVIITEGAGQGLERCRRFLANKSPEAARRAAQAIERQFLLLETTPAIGRPFPEQPEWRELVIEFGDSGYVALYRHEPA
DDAVYVLAFRHQKEAGY

Download         Length: 294 bp

>T107260 NZ_CP030165:c33753-33460 [Xanthomonas citri pv. punicae]
GTGCCACACGTAATCATCACCGAAGGCGCGGGCCAAGGGTTGGAGCGCTGTCGGCGCTTTCTGGCCAACAAGAGCCCAGA
GGCAGCCCGACGGGCCGCCCAAGCCATCGAGCGACAGTTCTTGCTGCTAGAAACGACCCCGGCCATAGGTCGCCCTTTTC
CTGAGCAACCGGAGTGGCGCGAGCTGGTCATTGAATTCGGTGATTCCGGCTATGTGGCCTTGTACCGCCACGAGCCTGCA
GATGATGCCGTCTACGTGCTGGCCTTCCGGCACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10484.62 Da        Isoelectric Point: 6.0804

>AT107260 WP_005933973.1 NZ_CP030165:c34013-33741 [Xanthomonas citri pv. punicae]
MATSLKIDDELKGRVQHLASLRDRSPHWIMREAIKQYVEREEARESFKQEAQASWTAYQETGRHLTGQEVRAWLSTWGTD
NETGLPECHT

Download         Length: 273 bp

>AT107260 NZ_CP030165:c34013-33741 [Xanthomonas citri pv. punicae]
ATGGCAACGTCACTCAAAATCGACGACGAGCTGAAAGGGCGCGTGCAGCACCTGGCCAGCCTGCGCGATAGGTCGCCACA
CTGGATCATGCGTGAGGCGATCAAGCAGTACGTCGAGCGTGAGGAAGCGCGCGAAAGCTTCAAGCAGGAGGCGCAGGCGT
CCTGGACGGCCTATCAGGAAACCGGCCGGCATTTGACCGGGCAAGAAGTGCGCGCGTGGTTGAGCACTTGGGGCACAGAT
AACGAAACGGGACTGCCTGAGTGCCACACGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6M2VVM8

Antitoxin

Source ID Structure
AlphaFold DB A0A6M2VW75

References