107259

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4638045..4638406 Replicon chromosome
Accession NZ_CP030164
Organism Xanthomonas citri pv. punicae strain LMG7439

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XapA_RS20980 Protein ID WP_005914328.1
Coordinates 4638045..4638179 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XapA_RS20985 Protein ID WP_003486606.1
Coordinates 4638254..4638406 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XapA_RS20960 4633196..4634887 - 1692 Protein_3900 M20/M25/M40 family metallo-hydrolase -
XapA_RS20965 4635079..4636113 - 1035 WP_050550551.1 MBL fold metallo-hydrolase -
XapA_RS20970 4636152..4637441 - 1290 WP_003486598.1 tryptophan--tRNA ligase -
XapA_RS20975 4637609..4637818 - 210 WP_003486601.1 CsbD family protein -
XapA_RS20980 4638045..4638179 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XapA_RS20985 4638254..4638406 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XapA_RS20990 4638513..4639436 - 924 WP_005927745.1 arginase -
XapA_RS20995 4639757..4640209 + 453 WP_005927742.1 roadblock/LC7 domain-containing protein -
XapA_RS21000 4640273..4640632 + 360 WP_003486613.1 hypothetical protein -
XapA_RS21005 4640729..4641646 + 918 WP_005927739.1 hypothetical protein -
XapA_RS21010 4641643..4642185 + 543 WP_003486615.1 GTPase -
XapA_RS21020 4642623..4643306 + 684 WP_005927736.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T107259 WP_005914328.1 NZ_CP030164:c4638179-4638045 [Xanthomonas citri pv. punicae]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T107259 NZ_CP030164:c4638179-4638045 [Xanthomonas citri pv. punicae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT107259 WP_003486606.1 NZ_CP030164:c4638406-4638254 [Xanthomonas citri pv. punicae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT107259 NZ_CP030164:c4638406-4638254 [Xanthomonas citri pv. punicae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References