Detailed information of TA system TA107155

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 153188..154712
• Replicon: plasmid unnamed3
• Accession: NZ_CP030129
• Organism: Indioceanicola profundi strain SCSIO 08040

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: DOL89_RS24045
• Protein ID: WP_119681895.1
• Coordinates: 153188..154099 (-)
• Length: 304 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: DOL89_RS24050
• Protein ID: WP_119681896.1
• Coordinates: 154089..154712 (-)
• Length: 208 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DOL89_RS24030	149362..150158	-	797	Protein_137	TIGR02391 family protein	-
DOL89_RS24035	150206..151768	-	1563	WP_119681894.1	hypothetical protein	-
DOL89_RS24040	151758..153215	-	1458	WP_119682016.1	toll/interleukin-1 receptor domain-containing protein	-
DOL89_RS24045	153188..154099	-	912	WP_119681895.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
DOL89_RS24050	154089..154712	-	624	WP_119681896.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
DOL89_RS24055	154811..156202	-	1392	WP_119681897.1	hypothetical protein	-
DOL89_RS24060	156713..157399	+	687	WP_119682017.1	hypothetical protein	-
DOL89_RS24065	157503..158693	-	1191	WP_119681898.1	site-specific integrase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..296136	296136

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-257)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (16-56)

Sequences

Toxin

Protein

• Length: 304 a.a.
• Molecular weight: 33523.21 Da
• Isoelectric Point: 4.9796

>T107155 WP_119681895.1 NZ_CP030129:c154099-153188 [Indioceanicola profundi]
MAREVRNVGASVRARLLDRARTEKTDFQILLTRYALERLLYRLSVSDQRERFVLKGAMLFAAWRDDPFRPTRDLDLLGHG
DADPAAVAKSVRAICTVAVPDDGVVFDVAGIEAAPIRDEAEYAGVRVRTSATIAGARMPIQIDVGFGDAITPDPVEIEYP
ALLEAPRPVLRAYPPETVVAEKLEAIVSLGVANSRMKDFYDLWMIAQTFTFEGAVLANAVQQTFDRRRTSWPEQMPSGLG
EAFAGERDAQWRAFLTRDRLAAAPASLIQVTEDLRAFLLPVLERQQLASWSPGGPWTHTEAAS

Nucleotide

• Length: 912 bp

>T107155 NZ_CP030129:c154099-153188 [Indioceanicola profundi]
ATGGCGCGTGAGGTTCGCAATGTCGGTGCGTCGGTCCGTGCGCGGCTTCTCGATCGAGCCCGCACGGAGAAGACTGATTT
TCAGATTCTCCTCACGCGCTACGCGCTCGAGCGGCTGCTGTACCGCCTCAGTGTCTCCGATCAGCGCGAGCGGTTTGTCC
TGAAAGGGGCGATGCTCTTCGCCGCATGGCGGGACGATCCCTTCCGTCCCACCCGCGACCTCGATCTGCTGGGTCATGGC
GATGCCGATCCCGCTGCGGTCGCCAAGAGCGTCCGGGCCATCTGCACTGTGGCGGTGCCTGATGATGGCGTCGTCTTCGA
CGTCGCCGGCATCGAAGCCGCCCCAATCCGCGACGAGGCCGAATATGCCGGCGTGCGTGTCAGGACCAGCGCCACCATCG
CCGGCGCGCGCATGCCCATCCAGATCGATGTCGGGTTCGGCGATGCCATCACCCCCGACCCGGTTGAGATCGAGTACCCG
GCGCTGCTCGAAGCGCCGCGCCCGGTTCTGCGCGCCTATCCGCCCGAGACGGTGGTCGCCGAAAAGCTGGAGGCGATCGT
TTCGCTCGGCGTCGCCAACAGCCGGATGAAGGATTTCTACGACCTCTGGATGATCGCGCAGACGTTCACTTTCGAAGGCG
CCGTCCTCGCGAATGCTGTCCAACAGACGTTCGACCGCCGCCGGACATCCTGGCCCGAACAAATGCCCTCCGGCCTCGGC
GAGGCCTTTGCCGGCGAGCGGGATGCTCAGTGGCGTGCTTTTCTGACGCGCGATCGACTCGCGGCGGCGCCCGCTTCGCT
CATTCAAGTGACCGAAGATCTGCGGGCATTCTTGCTGCCTGTGCTGGAACGGCAGCAGCTTGCATCGTGGTCGCCCGGCG
GTCCCTGGACGCACACGGAGGCTGCCTCTTGA

Antitoxin

Protein

• Length: 208 a.a.
• Molecular weight: 23392.09 Da
• Isoelectric Point: 10.2519

>AT107155 WP_119681896.1 NZ_CP030129:c154712-154089 [Indioceanicola profundi]
MSPQPRTQRDTARDLFGEKGLVRMRDLREAGIGSETVARLVREGEITRVARGLYQLADSIPDARRSFAEASALVPRGVIC
LTSALQFHELTLQMPSAVWIAIDRTGWKPTVEYPPIRFVRFSSRALKEGVKRHLIDGIEVPIFEPAKTIVDCFRYRNKIG
LDIALEGLREALRTKRATPDQLWEFARAARVWSVMRPYVEAMVADGA

Nucleotide

• Length: 624 bp

>AT107155 NZ_CP030129:c154712-154089 [Indioceanicola profundi]
ATGTCACCCCAACCGAGGACCCAACGTGATACGGCCCGCGACCTCTTCGGCGAAAAGGGGCTGGTCCGTATGCGCGATCT
GCGCGAAGCAGGCATCGGATCCGAGACCGTTGCCCGCCTGGTTCGTGAAGGCGAGATCACGCGCGTGGCACGCGGACTTT
ACCAACTGGCCGACTCCATACCGGACGCCCGGCGCAGCTTCGCGGAGGCTTCCGCTCTCGTGCCCCGAGGAGTCATCTGC
CTCACATCAGCGCTGCAGTTTCATGAGCTGACACTGCAGATGCCATCTGCGGTGTGGATTGCAATCGACCGCACCGGCTG
GAAGCCCACCGTCGAATACCCGCCGATCCGTTTTGTCCGCTTCAGCAGCCGCGCACTCAAGGAGGGCGTGAAGCGACACC
TGATCGATGGCATCGAGGTGCCGATCTTCGAACCCGCCAAGACGATCGTCGATTGCTTCCGGTATCGCAACAAGATCGGT
CTCGACATCGCGCTGGAGGGGCTGCGCGAAGCGCTGCGAACAAAGCGGGCAACTCCAGACCAGCTCTGGGAATTCGCGCG
CGCAGCCCGCGTCTGGTCGGTGATGCGCCCCTACGTCGAAGCGATGGTCGCCGATGGCGCGTGA