Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 2868979..2869577 Replicon chromosome
Accession NZ_CP030126
Organism Indioceanicola profundi strain SCSIO 08040

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag DOL89_RS13705 Protein ID WP_119679653.1
Coordinates 2869221..2869577 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag DOL89_RS13700 Protein ID WP_119679652.1
Coordinates 2868979..2869224 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DOL89_RS13675 2864689..2864889 - 201 WP_119679649.1 sulfur carrier protein ThiS -
DOL89_RS13680 2865043..2866194 - 1152 WP_119679650.1 glycine oxidase ThiO -
DOL89_RS13685 2866362..2866901 - 540 WP_205574588.1 GNAT family N-acetyltransferase -
DOL89_RS13695 2867549..2868619 + 1071 WP_119679651.1 hypothetical protein -
DOL89_RS13700 2868979..2869224 + 246 WP_119679652.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
DOL89_RS13705 2869221..2869577 + 357 WP_119679653.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
DOL89_RS13710 2869597..2870811 + 1215 WP_119680435.1 DNA replication/repair protein RecF -
DOL89_RS13715 2870942..2873647 + 2706 WP_119679654.1 DNA topoisomerase (ATP-hydrolyzing) subunit B -
DOL89_RS13720 2873830..2874087 - 258 WP_119679655.1 toxin-antitoxin system HicB family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-116)

Antitoxin

Antitoxin PemI-like

(1-79)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 12736.66 Da        Isoelectric Point: 6.9519

>T107152 WP_119679653.1 NZ_CP030126:2869221-2869577 [Indioceanicola profundi]
MSLPEPDYAPEAGDLIWTDFDSRTGGGQGGRRPAVVLSARAFWEISRLCIVCPVTSGVRPFPTSVVLPDGLGIAGEVLTS
HVRSIDTLARPVRFSGRPLPERVLNELRAKLAALIGWE

Download         Length: 357 bp

>T107152 NZ_CP030126:2869221-2869577 [Indioceanicola profundi]
ATGAGCCTGCCGGAACCCGATTACGCGCCGGAGGCCGGAGACCTGATCTGGACCGACTTCGATTCCCGCACCGGAGGCGG
ACAGGGCGGCCGCAGGCCCGCCGTGGTGCTGTCCGCCCGCGCCTTCTGGGAGATCAGCCGGTTGTGCATCGTCTGCCCCG
TGACGTCCGGGGTGCGCCCGTTCCCGACCAGCGTGGTGCTGCCGGACGGGCTGGGCATCGCTGGAGAGGTGCTGACCAGC
CATGTCCGCAGCATCGACACGCTGGCGCGGCCGGTCCGTTTCAGCGGCCGCCCGCTGCCGGAGCGGGTCCTGAACGAGTT
GCGGGCGAAACTGGCCGCCCTGATCGGGTGGGAGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8844.12 Da        Isoelectric Point: 4.7527

>AT107152 WP_119679652.1 NZ_CP030126:2868979-2869224 [Indioceanicola profundi]
MKARVARWGNSLGIRIPRDVAGGVGLVEGSMVEIATENGRIVIDPGRPRYRLDDLLHGMKPGEMAGIYDWGPDLGQEIVD
E

Download         Length: 246 bp

>AT107152 NZ_CP030126:2868979-2869224 [Indioceanicola profundi]
ATGAAGGCGCGCGTGGCCCGTTGGGGCAACAGCCTTGGCATCCGCATTCCGCGCGACGTGGCGGGCGGGGTCGGGCTGGT
GGAAGGCAGTATGGTTGAGATCGCGACGGAGAATGGCCGCATCGTGATCGATCCCGGCCGCCCGCGCTATCGGCTGGACG
ATCTGCTGCACGGCATGAAGCCGGGCGAAATGGCCGGCATCTATGATTGGGGTCCCGATCTGGGGCAGGAAATCGTCGAC
GAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References