Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 2433025..2433488 Replicon chromosome
Accession NZ_CP030126
Organism Indioceanicola profundi strain SCSIO 08040

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DOL89_RS11630 Protein ID WP_119679308.1
Coordinates 2433213..2433488 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DOL89_RS11625 Protein ID WP_119679307.1
Coordinates 2433025..2433213 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DOL89_RS11595 2429664..2429888 + 225 WP_119679301.1 hypothetical protein -
DOL89_RS11600 2429879..2430217 - 339 WP_119679302.1 Rieske (2Fe-2S) protein -
DOL89_RS11605 2430220..2431035 - 816 WP_119679303.1 class I SAM-dependent methyltransferase -
DOL89_RS11610 2431047..2431460 - 414 WP_119679304.1 EVE domain-containing protein -
DOL89_RS11615 2431514..2431798 - 285 WP_119679305.1 YciI family protein -
DOL89_RS11620 2431906..2432898 - 993 WP_119679306.1 NAD(P)-dependent glycerol-3-phosphate dehydrogenase -
DOL89_RS11625 2433025..2433213 + 189 WP_119679307.1 stability determinant Antitoxin
DOL89_RS11630 2433213..2433488 + 276 WP_119679308.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DOL89_RS11635 2433495..2434568 - 1074 WP_119680384.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD -
DOL89_RS11640 2434652..2435617 + 966 WP_119680385.1 hydroxymethylbilane synthase -
DOL89_RS11645 2435608..2436339 + 732 WP_119679309.1 uroporphyrinogen-III synthase -
DOL89_RS11650 2436420..2438123 + 1704 WP_119679310.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10432.09 Da        Isoelectric Point: 8.5041

>T107151 WP_119679308.1 NZ_CP030126:2433213-2433488 [Indioceanicola profundi]
MLPIIWSPAARRKLDQIIGFILERNPTAAEELLERLETSVLPASSYPYIFRAGRVPGTREIVAHPNYIVVYAVRADHIEI
VTVHHARERYP

Download         Length: 276 bp

>T107151 NZ_CP030126:2433213-2433488 [Indioceanicola profundi]
ATGCTGCCGATCATCTGGAGTCCGGCGGCACGCCGTAAGCTCGACCAGATCATCGGCTTCATCCTGGAGCGGAATCCGAC
CGCGGCAGAGGAGTTGCTGGAGCGGCTGGAAACGTCCGTGCTTCCGGCCTCGTCATACCCGTACATTTTCAGGGCGGGCA
GGGTTCCCGGCACACGGGAGATCGTGGCGCACCCCAACTATATCGTCGTCTATGCCGTGCGCGCCGACCACATAGAAATC
GTCACGGTGCATCACGCCCGCGAAAGATACCCCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7011.84 Da        Isoelectric Point: 4.7661

>AT107151 WP_119679307.1 NZ_CP030126:2433025-2433213 [Indioceanicola profundi]
MDTYSPIESEFPSAQEAEEYDRWFRAEVEAALKETGPRAPHDQVMAEMRAKIAAAKARLGRT

Download         Length: 189 bp

>AT107151 NZ_CP030126:2433025-2433213 [Indioceanicola profundi]
ATGGACACCTATTCGCCCATCGAATCGGAATTCCCCTCCGCGCAGGAGGCGGAGGAGTATGACCGCTGGTTCCGTGCGGA
AGTCGAGGCTGCGCTGAAAGAGACCGGCCCCCGCGCACCCCATGACCAGGTCATGGCCGAGATGCGGGCCAAGATCGCCG
CAGCGAAAGCCCGCCTCGGGCGGACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References