Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2241727..2242400 Replicon chromosome
Accession NZ_CP030126
Organism Indioceanicola profundi strain SCSIO 08040

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DOL89_RS10725 Protein ID WP_205574561.1
Coordinates 2242002..2242400 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DOL89_RS10720 Protein ID WP_119679144.1
Coordinates 2241727..2242005 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DOL89_RS10695 2236790..2236951 + 162 WP_119679140.1 YqaE/Pmp3 family membrane protein -
DOL89_RS10700 2236960..2237346 + 387 WP_119680368.1 DUF4112 domain-containing protein -
DOL89_RS10705 2237461..2238093 + 633 WP_119679141.1 hypothetical protein -
DOL89_RS10710 2238735..2240009 + 1275 WP_119679142.1 type III PLP-dependent enzyme -
DOL89_RS10715 2240198..2241619 + 1422 WP_119679143.1 homospermidine synthase -
DOL89_RS10720 2241727..2242005 + 279 WP_119679144.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
DOL89_RS10725 2242002..2242400 + 399 WP_205574561.1 PIN domain-containing protein Toxin
DOL89_RS10730 2242532..2243686 + 1155 WP_119679145.1 ATP phosphoribosyltransferase regulatory subunit -
DOL89_RS10735 2243791..2245083 + 1293 WP_119679146.1 adenylosuccinate synthase -
DOL89_RS10740 2245205..2247238 + 2034 WP_119680370.1 serine/threonine protein kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin

Antitoxin VapB-like

(4-89)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14429.71 Da        Isoelectric Point: 5.1454

>T107150 WP_205574561.1 NZ_CP030126:2242002-2242400 [Indioceanicola profundi]
MIVLDTSILVAILLDEPEAERLRIILNDAPATILSAVNHFEARMLLRGRYGVPMLEKLDALLADLGTEIIAFDRRQSEAS
LQAFNRFGKGQGHPAQLNLADCCAYALAKTRGLPLLFKGGDFSQTDIQAAAY

Download         Length: 399 bp

>T107150 NZ_CP030126:2242002-2242400 [Indioceanicola profundi]
TTGATCGTCCTCGACACCTCGATCCTCGTCGCCATTCTGTTGGACGAACCTGAAGCAGAGCGGTTACGCATCATTCTGAA
CGACGCGCCGGCAACCATCCTGTCGGCCGTCAATCATTTCGAAGCCCGGATGCTGCTGCGCGGAAGGTATGGCGTCCCGA
TGCTGGAAAAGCTGGATGCGCTTCTGGCCGATCTGGGAACCGAAATCATCGCGTTCGACCGTCGGCAATCGGAAGCATCT
CTGCAAGCCTTCAACCGCTTCGGCAAAGGTCAGGGCCATCCGGCGCAGTTGAACCTGGCTGACTGCTGCGCCTATGCGCT
GGCGAAGACGCGCGGGCTGCCGCTGCTGTTCAAGGGCGGAGATTTCTCCCAAACGGATATCCAGGCCGCCGCCTATTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10261.53 Da        Isoelectric Point: 4.5482

>AT107150 WP_119679144.1 NZ_CP030126:2241727-2242005 [Indioceanicola profundi]
MGTMITTTEIDRLLSTLTAATGETPEQALARALEERIDRIGNPLRSHPLTEAERQARLERLRAISREASKLPVLDPRSDD
EILGYNDIGTFD

Download         Length: 279 bp

>AT107150 NZ_CP030126:2241727-2242005 [Indioceanicola profundi]
ATGGGCACCATGATCACCACCACGGAAATCGACCGCCTGTTGAGCACATTGACCGCTGCAACCGGTGAGACGCCCGAACA
GGCCCTGGCCCGCGCTCTTGAGGAGCGGATTGACAGGATCGGCAATCCCCTTCGCTCCCACCCCCTGACGGAAGCCGAGC
GCCAGGCTCGGCTGGAGCGGCTGCGCGCGATTTCGAGGGAGGCGTCTAAGCTTCCCGTTCTGGACCCACGCAGCGATGAC
GAGATCCTGGGCTATAACGATATCGGGACATTCGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References