Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 957861..958353 Replicon chromosome
Accession NZ_CP030125
Organism Streptococcus suis strain HA1003

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DP112_RS04830 Protein ID WP_114866477.1
Coordinates 958096..958353 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DP112_RS04825 Protein ID WP_114866476.1
Coordinates 957861..958112 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DP112_RS11075 953512..953649 + 138 WP_164503912.1 hypothetical protein -
DP112_RS04800 953662..954396 + 735 WP_114866472.1 beta-carotene 15,15'-monooxygenase -
DP112_RS04805 954495..954635 + 141 WP_114866473.1 hypothetical protein -
DP112_RS04810 954648..955037 + 390 WP_114866474.1 NisI/SpaI family lantibiotic immunity lipoprotein -
DP112_RS04815 955046..955798 + 753 WP_024407069.1 ABC transporter ATP-binding protein -
DP112_RS04820 955799..957769 + 1971 WP_114866475.1 FtsX-like permease family protein -
DP112_RS04825 957861..958112 + 252 WP_114866476.1 antitoxin Antitoxin
DP112_RS04830 958096..958353 + 258 WP_114866477.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DP112_RS04835 958392..959060 + 669 WP_161943640.1 response regulator transcription factor -
DP112_RS04840 959057..959998 + 942 WP_114866478.1 sensor histidine kinase -
DP112_RS04845 960074..961582 + 1509 WP_114866479.1 phosphomannomutase/phosphoglucomutase -
DP112_RS04855 961922..962992 - 1071 WP_114866480.1 tyrosine recombinase XerS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(10-75)

Antitoxin

Protein of unknown function DUF6290

(1-75)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9952.57 Da        Isoelectric Point: 11.0304

>T107144 WP_114866477.1 NZ_CP030125:958096-958353 [Streptococcus suis]
MKTSYKLVPTSRFIKQLKKLDKFTQKQITNYLSSHVTDNPRQYGKALTANRSGQWRYRIGNYRVIVSIEDDKLILTSLKM
RNGSI

Download         Length: 258 bp

>T107144 NZ_CP030125:958096-958353 [Streptococcus suis]
ATGAAGACCAGTTATAAACTCGTACCAACCAGTCGTTTTATCAAACAGTTGAAAAAGCTGGACAAATTTACTCAAAAGCA
GATTACCAACTACCTGTCCAGTCATGTGACTGACAACCCCAGACAATACGGAAAAGCTTTGACTGCCAATCGTTCTGGCC
AATGGCGGTATCGTATCGGAAATTACAGGGTCATCGTCAGTATTGAAGATGATAAATTGATTTTGACAAGCCTAAAAATG
AGAAATGGAAGTATATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9439.65 Da        Isoelectric Point: 3.7952

>AT107144 WP_114866476.1 NZ_CP030125:957861-958112 [Streptococcus suis]
MAAITLKVSEQDKLFMQAMAKFEGVSLSELIRTKTLEALEDEYDARVADIAWAEYQEDLANGIEPISWEKMLEELGLTDE
DQL

Download         Length: 252 bp

>AT107144 NZ_CP030125:957861-958112 [Streptococcus suis]
ATGGCAGCTATTACATTGAAAGTTTCTGAGCAGGACAAGCTCTTTATGCAGGCTATGGCAAAGTTTGAAGGTGTCAGCTT
GTCAGAACTCATTCGGACTAAAACCCTTGAAGCCCTTGAAGACGAATACGATGCGCGTGTGGCAGACATAGCCTGGGCAG
AATACCAAGAAGACTTGGCAAACGGCATTGAGCCGATAAGCTGGGAGAAAATGTTGGAAGAGTTGGGGTTGACGGATGAA
GACCAGTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References