Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 2005783..2006323 Replicon chromosome
Accession NZ_CP030104
Organism Flagellimonas maritima strain HME9304

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HME9304_RS08940 Protein ID WP_164674820.1
Coordinates 2005783..2006076 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HME9304_RS08945 Protein ID WP_112379777.1
Coordinates 2006069..2006323 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HME9304_RS08900 2001978..2002286 - 309 WP_206170458.1 hypothetical protein -
HME9304_RS08905 2002425..2002919 - 495 WP_112378256.1 hypothetical protein -
HME9304_RS08910 2002954..2003781 - 828 WP_164674816.1 alpha/beta hydrolase -
HME9304_RS08915 2003801..2004145 - 345 WP_123877420.1 hypothetical protein -
HME9304_RS08920 2004150..2004440 - 291 WP_112378259.1 barstar family protein -
HME9304_RS08925 2004459..2004836 - 378 WP_112378260.1 hypothetical protein -
HME9304_RS08930 2004841..2005431 - 591 WP_112378261.1 hypothetical protein -
HME9304_RS08935 2005460..2005768 - 309 WP_112378262.1 hypothetical protein -
HME9304_RS08940 2005783..2006076 - 294 WP_164674820.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HME9304_RS08945 2006069..2006323 - 255 WP_112379777.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HME9304_RS08950 2006496..2006879 - 384 WP_164674822.1 hypothetical protein -
HME9304_RS08955 2007248..2007919 - 672 WP_112378265.1 hypothetical protein -
HME9304_RS08960 2008189..2008422 - 234 WP_112378266.1 hypothetical protein -
HME9304_RS08965 2008435..2008779 - 345 WP_123877423.1 hypothetical protein -
HME9304_RS08970 2008828..2009181 - 354 WP_112378268.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1966047..2073157 107110


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Antitoxin ParD

(7-71)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11167.92 Da        Isoelectric Point: 9.8967

>T107102 WP_164674820.1 NZ_CP030104:c2006076-2005783 [Flagellimonas maritima]
MLSFQLTTTAESDIASIADYTIFKFGIGQARKYRDGLIDSFDQLASNPLLGRTFIMENQPGLKRFRYKSHVIFYRETNSG
ILIIRILGGMMNFERHL

Download         Length: 294 bp

>T107102 NZ_CP030104:c2006076-2005783 [Flagellimonas maritima]
ATGCTTAGTTTTCAACTGACCACAACAGCGGAATCGGATATAGCATCGATAGCCGATTATACTATTTTCAAGTTTGGTAT
TGGACAGGCTAGAAAATATAGGGATGGTTTGATAGATTCGTTTGACCAACTGGCTTCAAACCCTTTATTGGGCCGAACTT
TTATAATGGAAAATCAACCCGGTCTAAAAAGATTCAGATACAAGTCTCATGTAATATTTTACAGAGAAACCAATTCTGGA
ATTTTGATTATAAGAATTCTTGGCGGTATGATGAATTTTGAAAGACACTTATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9949.06 Da        Isoelectric Point: 5.7669

>AT107102 WP_112379777.1 NZ_CP030104:c2006323-2006069 [Flagellimonas maritima]
MTTIRKSITFTEQQDKWIKRQIEKGDYTNDSEYLRDLVRKDQADRQKLDELKAAIQEGLDSGISDKTVDEIWREAEERHA
KKHA

Download         Length: 255 bp

>AT107102 NZ_CP030104:c2006323-2006069 [Flagellimonas maritima]
ATGACTACAATTAGAAAATCCATCACCTTTACGGAACAACAAGATAAGTGGATAAAACGGCAAATCGAGAAAGGAGATTA
CACAAATGATAGTGAATATTTGAGAGACTTGGTACGCAAAGACCAAGCCGACCGGCAAAAATTAGATGAGCTCAAAGCGG
CCATTCAAGAGGGTCTTGATAGCGGAATAAGCGACAAGACAGTTGATGAGATATGGAGGGAAGCGGAAGAGCGACATGCT
AAAAAGCATGCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References