Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParST/RES-Xre
Location 6317907..6318712 Replicon chromosome
Accession NZ_CP030092
Organism Massilia sp. YMA4

Toxin (Protein)


Gene name ParT Uniprot ID -
Locus tag DPH57_RS27075 Protein ID WP_112940496.1
Coordinates 6318224..6318712 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name ParS Uniprot ID -
Locus tag DPH57_RS27070 Protein ID WP_112940940.1
Coordinates 6317907..6318227 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DPH57_RS27055 6313726..6314076 + 351 WP_112940493.1 cell division protein FtsB -
DPH57_RS27060 6314261..6316504 + 2244 WP_112940494.1 TonB-dependent receptor -
DPH57_RS27065 6316514..6317656 + 1143 WP_112940495.1 hemin-degrading factor -
DPH57_RS27070 6317907..6318227 + 321 WP_112940940.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
DPH57_RS27075 6318224..6318712 + 489 WP_112940496.1 RES family NAD+ phosphorylase Toxin
DPH57_RS27080 6318744..6319871 - 1128 WP_112940497.1 glycerophosphodiester phosphodiesterase -
DPH57_RS27085 6319871..6322252 - 2382 WP_112940498.1 TonB-dependent receptor plug domain-containing protein -
DPH57_RS27090 6322521..6323270 + 750 WP_112940499.1 thermostable hemolysin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(5-137)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(1-37)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17417.96 Da        Isoelectric Point: 9.4576

>T107038 WP_112940496.1 NZ_CP030092:6318224-6318712 [Massilia sp. YMA4]
MTRLLWRIAAVTPRYTAEDLSGKGAESTGGRWNAAGTPLVYTSSNIALASLETLARLGLEGVPLNRYLVRIDVPDHVYAA
RTVLAPPPGWDAQPYGLPSVQAGQAWCRAGATALLEVPSVLVPEEANVLINPRHPDSACLRATALRKWLVSYHRGQAPIS
GR

Download         Length: 489 bp

>T107038 NZ_CP030092:6318224-6318712 [Massilia sp. YMA4]
ATGACGCGCCTGCTGTGGCGCATCGCGGCGGTGACGCCGCGGTACACTGCCGAGGATTTGTCCGGCAAGGGCGCCGAGAG
CACGGGCGGGCGCTGGAACGCGGCCGGCACGCCGCTCGTCTACACGTCATCGAATATCGCGCTGGCGTCGCTGGAAACGC
TGGCCCGCCTGGGCCTGGAAGGCGTGCCGCTGAATCGCTACCTGGTACGCATCGACGTGCCGGACCACGTCTACGCCGCC
CGCACCGTGCTGGCGCCACCGCCCGGCTGGGACGCGCAGCCGTATGGCCTGCCCAGCGTGCAGGCCGGGCAGGCGTGGTG
CCGGGCCGGCGCGACGGCGCTGCTGGAAGTGCCTTCCGTGCTGGTGCCGGAGGAGGCCAATGTGCTGATCAATCCGCGCC
ACCCGGACAGCGCGTGCCTGCGCGCCACGGCGCTGCGCAAGTGGCTGGTGAGCTACCACCGGGGACAGGCACCGATCTCA
GGGCGGTAA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11103.69 Da        Isoelectric Point: 4.3466

>AT107038 WP_112940940.1 NZ_CP030092:6317907-6318227 [Massilia sp. YMA4]
MSKESLLDALGIARATLSRKVRGNLPLAPDESERVLGVQALIGQVQAMVAEAEAPEDFDAAAWMSRWLTTPLAALGGATP
ASYLDTVEGQKYIANLLAMAQGGAYA

Download         Length: 321 bp

>AT107038 NZ_CP030092:6317907-6318227 [Massilia sp. YMA4]
ATGTCGAAGGAGAGCCTGCTCGATGCGCTGGGCATTGCGCGCGCCACGCTGAGCCGCAAGGTGCGCGGGAACCTGCCGCT
GGCGCCGGACGAATCCGAGCGCGTGCTGGGCGTGCAGGCCCTGATCGGGCAGGTGCAGGCGATGGTGGCGGAGGCGGAAG
CACCGGAAGACTTCGATGCCGCCGCGTGGATGTCGCGCTGGCTGACCACGCCGCTGGCCGCGCTGGGCGGCGCCACCCCG
GCCAGCTACCTCGACACCGTGGAAGGCCAGAAATACATCGCCAACCTGCTTGCGATGGCGCAGGGCGGAGCCTATGCATG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References