Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 647335..647866 Replicon chromosome
Accession NZ_CP030086
Organism Polynucleobacter paneuropaeus strain MWH-Creno-4B4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DPM16_RS03370 Protein ID WP_112203740.1
Coordinates 647335..647616 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag DPM16_RS03375 Protein ID WP_112318201.1
Coordinates 647603..647866 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DPM16_RS03355 644695..645198 + 504 WP_112203734.1 DUF1993 domain-containing protein -
DPM16_RS03360 645219..646175 - 957 WP_112294736.1 tripartite tricarboxylate transporter substrate binding protein -
DPM16_RS03365 646172..647239 - 1068 WP_112209113.1 tartrate dehydrogenase -
DPM16_RS03370 647335..647616 - 282 WP_112203740.1 type II toxin-antitoxin system YafQ family toxin Toxin
DPM16_RS03375 647603..647866 - 264 WP_112318201.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DPM16_RS03380 647981..648466 + 486 WP_112318202.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
DPM16_RS03385 648463..649752 + 1290 WP_112318203.1 Y-family DNA polymerase -
DPM16_RS03390 650049..650501 + 453 WP_112318204.1 Smr/MutS family protein -
DPM16_RS03395 650816..651118 + 303 WP_112318205.1 BrnT family toxin -
DPM16_RS03400 651078..651389 + 312 WP_112203751.1 BrnA antitoxin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-71)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11474.14 Da        Isoelectric Point: 9.2930

>T107034 WP_112203740.1 NZ_CP030086:c647616-647335 [Polynucleobacter paneuropaeus]
MRTTEYTKKFRKDYKRELKGRYRLTLARDFQETLDYLINDWDLPYRYHDHPLVGDWVDHRDCHIKPDLVLIYRKPDQRIL
QLVRLGSHSELSL

Download         Length: 282 bp

>T107034 NZ_CP030086:c647616-647335 [Polynucleobacter paneuropaeus]
ATGCGGACGACTGAATACACCAAAAAATTTAGAAAAGATTACAAAAGAGAATTAAAAGGTAGGTACCGACTTACGCTAGC
TAGAGATTTTCAGGAAACTTTAGATTACTTAATTAATGACTGGGATCTTCCTTATCGATACCACGACCACCCCTTAGTGG
GGGACTGGGTGGACCATAGAGACTGTCATATCAAACCCGATTTAGTCCTCATCTACAGAAAACCGGATCAGCGCATCCTT
CAATTGGTTCGACTAGGATCACATAGCGAATTAAGCTTATAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9407.82 Da        Isoelectric Point: 4.7571

>AT107034 WP_112318201.1 NZ_CP030086:c647866-647603 [Polynucleobacter paneuropaeus]
MTANAVVRARINGDIKEEASAILAAMGLTPSDAFRILMTRIAREKTLPFEPLSPNAETIAAMKEARKGNLKSFTSIDDLM
ADLNADD

Download         Length: 264 bp

>AT107034 NZ_CP030086:c647866-647603 [Polynucleobacter paneuropaeus]
ATGACCGCAAACGCAGTAGTTCGCGCCAGAATTAACGGCGATATCAAAGAGGAAGCTAGTGCCATATTGGCTGCTATGGG
TCTAACGCCGTCTGATGCCTTTCGAATTCTGATGACCCGCATAGCCAGAGAAAAGACTCTGCCCTTTGAACCATTAAGTC
CCAACGCAGAAACGATTGCTGCGATGAAAGAAGCTAGAAAAGGAAATCTCAAATCCTTTACTTCTATTGACGACTTGATG
GCTGACCTGAATGCGGACGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References