Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3284443..3284588 Replicon chromosome
Accession NZ_CP030070
Organism Klebsiella pneumoniae strain IA565

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3284450..3284552 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3284443..3284588 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DPF99_RS18195 3279975..3281408 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DPF99_RS18200 3281524..3281763 + 240 WP_002911393.1 YebV family protein -
DPF99_RS18205 3281861..3282052 + 192 WP_002911395.1 YebW family protein -
DPF99_RS18210 3282049..3282702 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
DPF99_RS18215 3282859..3283827 + 969 WP_004151446.1 VirK/YbjX family protein -
DPF99_RS18220 3283932..3284075 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3284443..3284588 + 146 - - Antitoxin
- 3284450..3284552 - 103 - - Toxin
DPF99_RS18230 3284711..3285049 - 339 WP_032445207.1 YebY family protein -
DPF99_RS18235 3285066..3285935 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
DPF99_RS18240 3285939..3286313 - 375 WP_004151448.1 CopC domain-containing protein YobA -
DPF99_RS18245 3286426..3286656 + 231 WP_002911406.1 DNA polymerase III subunit theta -
DPF99_RS18250 3286735..3287394 + 660 WP_002911407.1 exodeoxyribonuclease X -
DPF99_RS18255 3287398..3289458 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T106979 NZ_CP030070:c3284552-3284450 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT106979 NZ_CP030070:3284443-3284588 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References