Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2472803..2473443 Replicon chromosome
Accession NZ_CP030059
Organism Bradyrhizobium sp. CCBAU 53351

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag XH83_RS11560 Protein ID WP_194407116.1
Coordinates 2473153..2473443 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag XH83_RS11555 Protein ID WP_194407115.1
Coordinates 2472803..2473153 (-) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH83_RS11540 2468032..2471148 + 3117 WP_194407112.1 CusA/CzcA family heavy metal efflux RND transporter -
XH83_RS11545 2471152..2472114 - 963 WP_194407113.1 amidohydrolase family protein -
XH83_RS11550 2472165..2472722 - 558 WP_194407114.1 hypothetical protein -
XH83_RS11555 2472803..2473153 - 351 WP_194407115.1 putative addiction module antidote protein Antitoxin
XH83_RS11560 2473153..2473443 - 291 WP_194407116.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XH83_RS11565 2473549..2474946 - 1398 WP_194407117.1 TolC family outer membrane protein -
XH83_RS11570 2475167..2475946 - 780 WP_194407118.1 enoyl-CoA hydratase -
XH83_RS11575 2476093..2476758 - 666 WP_194407119.1 hypothetical protein -
XH83_RS11580 2477043..2477588 + 546 WP_194407120.1 sigma-70 family RNA polymerase sigma factor -
XH83_RS11585 2477591..2478229 + 639 WP_194407121.1 DUF1109 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-92)

Antitoxin

Uncharacterized protein HI1420

(12-106)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11067.79 Da        Isoelectric Point: 10.3398

>T106966 WP_194407116.1 NZ_CP030059:c2473443-2473153 [Bradyrhizobium sp. CCBAU 53351]
MIEVRQTELFSEWLNRLKDASAVARITVRLRRMEMGNPGDSKGVGHNIREMRIDHGPGYRIYYVQRGTQIVILLCGGDKR
TQRQDIKLAQQLAETL

Download         Length: 291 bp

>T106966 NZ_CP030059:c2473443-2473153 [Bradyrhizobium sp. CCBAU 53351]
ATGATCGAGGTGAGGCAGACCGAGCTTTTTTCGGAGTGGCTGAATCGCCTCAAGGACGCGAGCGCGGTTGCCCGTATCAC
CGTCCGCCTTCGCCGCATGGAGATGGGTAATCCTGGCGACAGCAAGGGCGTCGGCCACAACATCCGGGAAATGCGCATCG
ACCACGGTCCGGGCTACCGGATCTATTATGTGCAGCGCGGAACGCAGATCGTGATCCTGCTATGTGGCGGCGACAAACGC
ACGCAGCGACAGGACATCAAGCTAGCTCAGCAACTAGCGGAGACATTGTGA

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 12218.99 Da        Isoelectric Point: 10.6817

>AT106966 WP_194407115.1 NZ_CP030059:c2473153-2472803 [Bradyrhizobium sp. CCBAU 53351]
MPKAAKTAVKAASKTTRFDAADYLDTEERQAAYIAAALETGDADFVRDALGLVARARGMSTIAKKAGLNRESLYKALGET
GNPEFGTVMRIVAALGLTLSAQLATSGRATKRRRAA

Download         Length: 351 bp

>AT106966 NZ_CP030059:c2473153-2472803 [Bradyrhizobium sp. CCBAU 53351]
ATGCCGAAAGCAGCAAAAACGGCGGTCAAAGCGGCATCCAAGACGACGCGCTTCGATGCCGCCGACTATCTCGACACTGA
AGAGCGCCAAGCCGCCTATATTGCCGCCGCGCTGGAAACCGGTGACGCCGATTTCGTGCGCGACGCCCTCGGTCTCGTTG
CGCGTGCGCGCGGCATGAGCACCATCGCCAAAAAAGCCGGCTTGAACCGCGAAAGCCTGTATAAGGCCCTCGGAGAGACG
GGAAATCCCGAGTTCGGCACGGTCATGCGCATTGTCGCGGCGTTGGGCCTGACATTGTCGGCTCAACTCGCGACCAGCGG
ACGAGCGACGAAGCGCCGCCGCGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References