Detailed information of TA system TA106965

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 1660239..1660888
• Replicon: chromosome
• Accession: NZ_CP030059
• Organism: Bradyrhizobium sp. CCBAU 53351

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: XH83_RS07940
• Protein ID: WP_194406464.1
• Coordinates: 1660490..1660888 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: XH83_RS07935
• Protein ID: WP_194406463.1
• Coordinates: 1660239..1660493 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XH83_RS39610	1655577..1656011	+	435	WP_210347007.1	hypothetical protein	-
XH83_RS07910	1656208..1656450	-	243	WP_194406458.1	helix-turn-helix transcriptional regulator	-
XH83_RS07915	1656633..1657148	+	516	WP_194406459.1	hypothetical protein	-
XH83_RS07920	1657573..1658220	+	648	WP_194406460.1	hypothetical protein	-
XH83_RS07925	1658229..1658744	+	516	WP_194406461.1	hypothetical protein	-
XH83_RS07930	1658849..1660159	+	1311	WP_194406462.1	ParB N-terminal domain-containing protein	-
XH83_RS07935	1660239..1660493	+	255	WP_194406463.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
XH83_RS07940	1660490..1660888	+	399	WP_194406464.1	type II toxin-antitoxin system VapC family toxin	Toxin
XH83_RS07945	1661222..1661641	+	420	WP_194406465.1	hypothetical protein	-
XH83_RS07950	1662011..1662487	+	477	WP_194406466.1	cupin domain-containing protein	-
XH83_RS07955	1662591..1663943	-	1353	WP_194406467.1	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1656633..1688593	31960
	-	flank	IS/Tn	-	-	1662591..1663943	1352

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-125)

Antitoxin

• Antitoxin VapB-like (1-83)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 14337.31 Da
• Isoelectric Point: 4.9344

>T106965 WP_194406464.1 NZ_CP030059:1660490-1660888 [Bradyrhizobium sp. CCBAU 53351]
MIVDTSALIAILRNEPEAQRCALAIETHPIRRMSAANFVEAAVVIDASRDPIASRRFDELMKEAQISIEPVTEIQAQIAR
EAYRDFGKGSGHAAKLNFGDCFAYALAKSTGEPLLFKGDDFVHTDVVVASGT

Nucleotide

• Length: 399 bp

>T106965 NZ_CP030059:1660490-1660888 [Bradyrhizobium sp. CCBAU 53351]
ATGATTGTCGATACATCCGCGCTCATTGCGATCCTGCGGAACGAGCCAGAGGCACAGCGTTGCGCGCTTGCGATTGAAAC
TCATCCCATTCGACGGATGTCCGCTGCAAATTTCGTCGAGGCCGCTGTTGTGATCGATGCTAGCCGGGATCCAATCGCCA
GCCGCCGTTTCGATGAGTTGATGAAGGAAGCGCAGATTTCGATCGAGCCCGTAACTGAAATCCAGGCGCAAATTGCCCGA
GAGGCCTATCGGGATTTCGGCAAGGGCAGCGGTCATGCTGCTAAGCTGAATTTCGGTGACTGCTTTGCCTACGCACTCGC
CAAGAGCACTGGTGAGCCTTTGCTGTTTAAGGGCGATGATTTCGTCCATACGGATGTCGTTGTTGCCAGCGGTACTTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9499.71 Da
• Isoelectric Point: 8.0636

>AT106965 WP_194406463.1 NZ_CP030059:1660239-1660493 [Bradyrhizobium sp. CCBAU 53351]
MSLNIKNSEAHELASELAKRTGESLTAAVTTAVRERLERVRREQGARLSDRLLKIGEDCAKHLKEPYRSADHGDLLYDER
GLPR

Nucleotide

• Length: 255 bp

>AT106965 NZ_CP030059:1660239-1660493 [Bradyrhizobium sp. CCBAU 53351]
ATGAGTTTAAACATCAAGAATTCCGAAGCCCATGAATTGGCGAGCGAGCTAGCAAAGCGGACCGGGGAGTCGTTGACTGC
GGCGGTTACGACTGCCGTTCGTGAGCGGCTCGAGCGGGTTCGCCGCGAACAGGGCGCACGTCTATCGGATCGTTTGCTGA
AGATCGGTGAGGACTGCGCCAAACACTTGAAAGAGCCCTACCGATCGGCTGATCACGGCGATCTGCTCTACGATGAACGC
GGACTGCCTCGATGA